Paper-Based Electrochemical Biosensors: From Test Strips to Paper-Based Microfluidics

被引:101
|
作者
Liu, Bingwen [1 ]
Du, Dan [2 ]
Hua, Xin [1 ]
Yu, Xiao-Ying [1 ]
Lin, Yuehe [1 ,2 ]
机构
[1] Pacific NW Natl Lab, Richland, WA 99352 USA
[2] Washington State Univ, Sch Mech & Mat Engn, Pullman, WA 99164 USA
基金
美国国家卫生研究院;
关键词
Electrochemical detection; Lateral flow test strip; Paper-based/paper microfluidics; Point-of-care diagnosis; Biosensors; LATERAL FLOW TEST; ULTRASENSITIVE MULTIPLEXED DETECTION; IMMUNOCHROMATOGRAPHIC TEST STRIP; PHOSPHORYLATED ACETYLCHOLINESTERASE; SENSITIVE DETECTION; NANOPARTICLE PROBE; RAPID DETECTION; LOW-COST; CHEMILUMINESCENCE IMMUNOASSAY; EXPOSURE BIOMARKER;
D O I
10.1002/elan.201400036
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Papers based biosensors such as lateral flow test strips and paper-based microfluidic devices are inexpensive, rapid, flexible, and easy-to-use analytical tools for point-of-care diagnosis. An apparent trend in their detection is to interpret sensing results from qualitative assessment to quantitative determination. Electrochemical (EC) detection plays an important role in quantifying test results. This review focuses on paper-based biosensors with EC detection. The first part provides detailed examples in lateral flow test strips while the second part gives an overview of paper microfluidics. The outlook and recommendation of future directions of papers based EC biosensors are discussed in the end.
引用
收藏
页码:1214 / 1223
页数:10
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