Data on molecular characterization and expression profiles of the NF-κB repressing factor gene in red sea bream (Pagrus major)

被引:0
|
作者
Choi, Kwang-Min [1 ]
Hwang, Jee Youn [2 ]
Kwon, Mun-Gyeong [2 ]
Jeong, Ji-Min [2 ]
Seo, Jung Soo [2 ]
Hwang, Seong Don [2 ]
Jee, Bo-Yeong [2 ]
Kim, Mu-Chan [1 ]
Park, Chan-Il [1 ]
机构
[1] Gyeongsang Natl Univ, Coll Marine Sci, Inst Marine Ind, Tongyeong 650160, South Korea
[2] NIFS, Aquat Anim Dis Control Ctr, 216 Gijanghaean Ro, Busan 46083, South Korea
来源
DATA IN BRIEF | 2019年 / 24卷
关键词
NF-kappa B repressing factor; Pagrus major; Streptococcus iniae; Red sea bream iridovirus;
D O I
10.1016/j.dib.2019.103977
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Nuclear factor-kappaB (NF-kappa B) repressing factor (NKRF) specifically inhibits the transcriptional activity of NF-kappa B protein. The PmNKRF cDNA is composed of 757 amino acid residues. Alignment analysis revealed that the G-patch and R3H domains are conserved in different organisms. We aimed to analyse red sea bream NKRF (PmNKRF) gene expression after infection with pathogens [Streptococcus iniae or red sea bream iridovirus (RSIV)] and in healthy individuals. In healthy individuals, PmNKRF was ubiquitously expressed in all 12 tested tissues, predominantly in the head kidney and spleen. Expression of PmNKRF was significantly upregulated in the gills, kidney, liver and spleen after RSIV infection. After S. iniae infection, PmNKRF expression was significantly down-regulated in the gills and significantly up-regulated in the kidney, liver and spleen. (C) 2019 The Author(s). Published by Elsevier Inc.
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页数:8
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