Attenuation of Regional Cerebral Blood Flow During Memory Processing After Coronary Artery Bypass Surgery

被引:1
|
作者
Badgaiyan, Rajendra D. [1 ]
Weise, Steven [2 ]
Wack, David S. [3 ]
Melo, Marcos F. Vidal [4 ,5 ]
机构
[1] SUNY Buffalo, Dept Psychiat, Buffalo, NY 14260 USA
[2] Massachusetts Gen Hosp, Dept Radiol, Boston, MA 02114 USA
[3] SUNY Buffalo, Dept Nucl Med, Buffalo, NY 14260 USA
[4] Massachusetts Gen Hosp, Dept Anesthesia Crit Care & Pain Med, Boston, MA 02114 USA
[5] Harvard Univ, Sch Med, Boston, MA USA
来源
ANESTHESIA AND ANALGESIA | 2014年 / 119卷 / 03期
关键词
OFF-PUMP; ON-PUMP; MODALITIES; VULNERABILITY;
D O I
10.1213/ANE.0000000000000334
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Reports of memory impairment after cardiac surgery are controversial. To address this controversy, we used positron emission tomography to examine changes in regional cerebral blood flow (rCBF) during memory processing before and after elective coronary artery bypass grafting surgery. In postoperative scans, we observed significantly reduced rCBF in 2 of the most important memory processing areas; the medial temporal lobe (P = 0.023) and the prefrontal cortex (P = 0.002). The results suggest postoperative attenuation of rCBF in brain areas involved in memory processing. These reductions could be used to evaluate severity of memory impairment after coronary artery bypass grafting surgery in patients at risk.
引用
收藏
页码:550 / 553
页数:4
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