A parallel Smith-Waterman algorithm based on divide and conquer

被引:0
|
作者
Zhang, F [1 ]
Qiao, XZ [1 ]
Liu, ZY [1 ]
机构
[1] Chinese Acad Sci, Comp Technol Inst, Beijing 100080, Peoples R China
关键词
biological sequence alignment; dynamic programming; divide and conquer; parallel;
D O I
暂无
中图分类号
TP3 [计算技术、计算机技术];
学科分类号
0812 ;
摘要
Biological sequence comparison is an important tool for researchers in molecular biology. There are several algorithms for sequence comparison. The Smith-Waterman algorithm, based on dynamic programming, is one of the most fundamental algorithms in bioinformatics. However the existing parallel Smith-Waterman algorithm needs large memory space. As the data of biological sequences expand rapidly, the memory requirement of the existing parallel Smith-Waterman algorithm has becoming a critical problem. For resolving this problem, we develop a new parallel Smith-Waterman algorithm using the method of divide and conquer, named PSW-DC Memory space required in the new parallel algorithm is reduced significantly in comparison with existing ones. A key technique, named The C&E method, is developed for the implementation of the new parallel Smith-Waterman algorithm.
引用
收藏
页码:162 / 169
页数:8
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