Efficacy and safety of PXT3003 in patients with Charcot-Marie-Tooth type 1A: Results of PLEO-CMT, an international pivotal phase 3 trial

被引：0
|
作者：
Thomas, Florian P.
Boutalbi, Youcef
Fitoussi, Serge
Rinaudo, Philippe
Bertrand, Viviane
Hajj, Rodolphe
Nabirotchkin, Serguei
Cohen, Daniel H.
机构：
来源：
NEUROLOGY | 2019年 / 93卷 / 05期
关键词：
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
引用
收藏
页码：E530 / E530
页数：1
相关论文
共 50 条
  • [1] Efficacy and safety of PXT3003 in patients with Charcot-Marie-Tooth type 1A (CMT1A): results of PLEO-CMT an International Pivotal Phase 3 trial. For the PLEO CMT Investigators
    Young, P.
    Attarian, S.
    Youcef, B.
    Rinaudo, P.
    Fitoussi, S.
    Bertrand, V.
    Hajj, R.
    Nabirotchkin, S.
    Cohen, D.
    [J]. EUROPEAN JOURNAL OF NEUROLOGY, 2019, 26 : 74 - 74
  • [2] EFFICACY AND SAFETY OF PXT3003 IN PATIENTS WITH CHARCOT-MARIE-TOOTH DISEASE TYPE 1A: RESULTS OF PLEO-CHARCOT-MARIE-TOOTH: AN INTERNATIONAL PIVOTAL PHASE III TRIAL
    Thomas, Florian
    Boutalbi, Youcef
    Fitoussi, Serge
    Rinaudo, Philippe
    Bertrand, Viviane
    Hajj, Rodolphe
    Nabirotchkin, Serguei
    Cohen, Daniel
    [J]. MUSCLE & NERVE, 2019, 60 : S46 - S46
  • [3] Status of the pivotal phase III study of PXT3003 for Charcot-Marie-Tooth Type 1A disease (CMT1A)
    Goedkoop, Rene
    Attarian, Sharam
    Young, Peter
    Sevilla, Teresa
    Van Damme, Philip
    de Visser, Marianne
    Thomas, Florian
    Roberts, Mark
    Foucquier, Julie
    Boutalbi, Youcef
    Cohen, Daniel
    [J]. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 2018, 23 (04) : 319 - 319
  • [4] LONG-TERM SAFETY AND EFFICACY OF PXT3003 IN PATIENTS WITH CHARCOT-MARIE-TOOTH DISEASE TYPE 1A
    Thomas, Florian P.
    Boutalbi, Youcef
    Rinaudo, Philippe
    Bertrand, Viviane
    Hajj, Rodolphe
    Nabirotchkine, Serguei
    Cohen, Daniel
    [J]. MUSCLE & NERVE, 2020, 62 : S39 - S39
  • [5] Synergy of baclofen, naltrexone and sorbitol (PXT3003) in Charcot-Marie-Tooth Type 1A (CMT1A)
    Laffaire, Julien
    Rinaudo, Philippe
    Bertrand, Viviane
    Schmitt, Peter
    Goedkoop, Rene
    Cohen, Daniel
    [J]. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 2018, 23 (04) : 335 - 335
  • [6] A Multicenter, Double-Blind, Placebo-Controlled, Pivotal Phase III Study (PLEO-CMT) of a Fixed Combination of Baclofen, Naltrexone and Sorbitol (PXT3003) for Charcot-Marie-Tooth Disease Type 1A (CMT1A)
    Attarian, S.
    Young, P.
    Sevilla, T.
    van Damme, P.
    Visser, M.
    Thomas, F.
    Roberts, M.
    Foucquier, J.
    Goedkoop, R.
    [J]. EUROPEAN JOURNAL OF NEUROLOGY, 2018, 25 : 372 - 372
  • [7] DESIGN OF THE NEXT PHASE III TRIAL AIMING TO CONFIRM EFFICACY AND SAFETY OF PXT3003 IN THE TREATMENT OF CHARCOT-MARIE-TOOTH DISEASE TYPE 1A
    Scart-Gres, C.
    Attarian, S.
    Magy, L.
    Van Paassen, B.
    Sereda, M. W.
    Young, P.
    Bertrand, V
    Mandel, J.
    Guedj, M.
    Comblath, D. R.
    Cohen, D.
    [J]. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 2015, 20 (02) : 226 - 226
  • [8] PXT3003, A FIXED COMBINATION OF BACLOFEN, NALTREXONE AND SORBITOL, FOR THE TREATMENT OF CHARCOT-MARIE-TOOTH DISEASE TYPE 1A (CMT1A): STATUS OF A MULTICENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED, PIVOTAL PHASE III STUDY (PLEO-CMT)
    Attarian, S.
    Sevilla, T.
    Van Damme, P.
    De Visser, M.
    Thomas, F. P.
    Roberts, M.
    Young, P.
    [J]. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 2017, 22 (03) : 412 - 413
  • [9] A double-blind, placebo-controlled, randomized trial of PXT3003 for the treatment of Charcot-Marie-Tooth type 1A
    Attarian, Shahram
    Young, Peter
    Brannagan, Thomas H.
    Adams, David
    Van Damme, Philip
    Thomas, Florian P.
    Casanovas, Carlos
    Tard, Celine
    Walter, Maggie C.
    Pereon, Yann
    Walk, David
    Stino, Amro
    de Visser, Marianne
    Verhamme, Camiel
    Amato, Anthony
    Carter, Gregory
    Magy, Laurent
    Statland, Jeffrey M.
    Felice, Kevin
    [J]. ORPHANET JOURNAL OF RARE DISEASES, 2021, 16 (01)
  • [10] THE COMBINATIONAL DRUG PXT3003 IMPROVES NEUROMUSCULAR FUNCTION IN AN ANIMAL MODEL OF CHARCOT-MARIE-TOOTH TYPE 1A DISEASE
    Prukop, T.
    Wernick, S.
    Adam, J.
    Zschuentzsch, J.
    Schmidt, J.
    Brureau, A.
    Foucquier, J.
    Guedj, M.
    Cholet, N.
    Nave, K. A.
    Nabirotchkin, S.
    Hajj, R.
    Cohen, D.
    Sereda, M. W.
    [J]. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, 2017, 22 (03) : 363 - 363
12345