Predicting Wear and Blood Metal Ion Levels in Metal-on-Metal Hip Resurfacing

被引:47
|
作者
Matthies, Ashley K. [1 ]
Henckel, Johann [1 ]
Cro, Suzie [2 ]
Suarez, Alexander [3 ]
Noble, Philip C. [3 ]
Skinner, John [1 ]
Hart, Alister J. [1 ]
机构
[1] Univ Coll London, Inst Orthopaed & Musculoskeletal Sci, Royal Natl Orthopaed Hosp, Stanmore HA7 4LP, Middx, England
[2] Inst Orthoped Res & Educ, Houston, TX USA
[3] MRC, Clin Trials Unit, Swindon, Wilts, England
基金
英国医学研究理事会;
关键词
metal-on-metal; hip resurfacing; retrievals; wear; metal ions; ARTICULAR SURFACE; VOLUMETRIC WEAR; EARLY FAILURE; REPLACEMENT; PATTERNS; ORIENTATION; PSEUDOTUMOR; COMPONENT; BEARINGS; VERSION;
D O I
10.1002/jor.22459
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Suboptimal component position and design are thought to lead to edge wear and raised blood metal ion levels in metal-on-metal hip resurfacing (MOM-HR). These factors are thought to influence the "contact patch to rim distance" (CPRD), and calculation of this distance may improve prediction of wear and blood metal ion levels. We measured blood cobalt and chromium ion levels and the wear rates of the bearing surfaces in 165 MOM-HR retrieval cases. We then determined the contribution and effect sizes of cup inclination and version angles, component size and design, and CPRD (calculated from case-specific data) on blood metal ion levels and component wear rates. Acetabular orientation explained between 16.3% and 28.5% of the variation in wear rates and metal ion levels, whereas component size and design explained between 7.3% and 21.8% of the variability. In comparison, CPRD explained up to 67.7% of the variability, significantly greater than any other variable (all p<0.0001). CPRD is a good predictor of wear and improves our understanding of wear performance and the mechanisms leading to edge loading. (C) 2013 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.
引用
收藏
页码:167 / 174
页数:8
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