Changes in antimicrobial resistance and outcomes of health care-associated infections

被引：20

作者：

Aydin, Mehtap ^{[1
]}

Azak, Emel ^{[2
]}

Bilgin, Huseyin ^{[3
]}

Menekse, Sirin ^{[4
]}

Asan, Ali ^{[5
]}

Mert, Habibe Tulin Elmaslar ^{[6
]}

Yulugkural, Zerrin ^{[6
]}

Altunal, Lutfiye Nilsun ^{[1
]}

Hatipoglu, Cigdem Ataman ^{[7
]}

Ertem, Gunay Tuncer ^{[7
]}

Altunok, Elif Sargin ^{[8
]}

Demirkaya, Melike Hamiyet ^{[9
]}

Ceviker, Sevil Alkan ^{[10
]}

Akgul, Fethiye ^{[11
]}

Memis, Zeynep ^{[12
]}

Konya, Petek ^{[13
]}

Azap, Alpay ^{[14
]}

Aydin, Gule ^{[14
]}

Korkmaz, Derya ^{[15
]}

Karakoc, Zehra Cagla ^{[16
]}

Yapar, Derya ^{[17
]}

Karakecili, Faruk ^{[18
]}

Gunal, Ozgur ^{[19
]}

Keske, Siran ^{[20
]}

Kapmaz, Mahir ^{[20
]}

Kader, Cigdem ^{[21
]}

Demirel, Aslihan ^{[22
]}

Ergonul, Onder ^{[20
]}

机构：

[1] Umraniye Res & Training Hosp Univ Hlth Sci, Dept Infect Dis & Clin Microbiol, Adem Yavuz Cd, TR-34764 Istanbul, Turkey

[2] Kocaeli Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Kocaeli, Turkey

[3] Marmara Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey

[4] Kartal Kosuyolu Res & Training Hosp, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey

[5] Univ Hlth Sci, Dept Infect Dis & Clin Microbiol, Bursa, Turkey

[6] Trakya Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Edirne, Turkey

[7] Univ Hlth Sci Ankara Res & Training Hosp, Dept Infect Dis & Clin Microbiol, Ankara, Turkey

[8] Gaziosmanpasa Res & Training Hosp, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey

[9] Baskent Univ, Dept Infect Dis & Clin Microbiol, Sch Med, Ankara, Turkey

[10] Kutahya Hlth Sci Univ, Evliya Celebi Res & Training Hosp, Kutahya, Turkey

[11] Batman State Hosp, Dept Infect Dis & Clin Microbiol, Batman, Turkey

[12] Istanbul Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey

[13] Afyonkarahisar Univ Hlth Sci, Dept Infect Dis & Clin Microbiol, Afyon, Turkey

[14] Ankara Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Ankara, Turkey

[15] Afyonkarahisar State Hosp, Dept Infect Dis & Clin Microbiol, Afyon, Turkey

[16] Istinye Univ, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey

[17] Hitit Univ, Dept Infect Dis & Clin Microbiol, Sch Med, Corum, Turkey

[18] Erzincan Binali Yildirim Univ, Dept Infect Dis & Clin Microbiol, Sch Med, Erzincan, Turkey

[19] Univ Hlth Sci Samsun Res & Training Hosp, Samsun, Turkey

[20] Koc Univ, Dept Infect Dis & Clin Microbiol, Sch Med, Istanbul, Turkey

[21] Bozok Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Yozgat, Turkey

[22] Florans Nightingale Hosp, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2021年 / 40卷 / 08期

关键词：

Health care; associated infections; Blood stream infections; Colistin resistance;

D O I：

10.1007/s10096-020-04140-y

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

To describe the change in the epidemiology of health care-associated infections (HAI), resistance and predictors of fatality we conducted a nationwide study in 24 hospitals between 2015 and 2018. The 30-day fatality rate was 22% in 2015 and increased to 25% in 2018. In BSI, a significant increasing trend was observed for Candida and Enterococcus. The highest rate of 30-day fatality was detected among the patients with pneumonia (32%). In pneumonia, Pseudomonas infections increased in 2018. Colistin resistance increased and significantly associated with 30-day fatality in Pseudomonas infections. Among S. aureus methicillin, resistance increased from 31 to 41%.

引用

页码：1737 / 1742

页数：6

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