Biofunctionalisation of electrically conducting polymers

被引：41

作者：

Vallejo-Giraldo, Catalina ^{[1
]}

Kelly, Adriona ^{[1
]}

Biggs, Manus J. P. ^{[1
]}

机构：

[1] Natl Univ Ireland, Network Excellence Funct Biomat NFB, Galway, Ireland

来源：

DRUG DISCOVERY TODAY | 2014年 / 19卷 / 01期

关键词：

CONTROLLED-RELEASE; POLYPYRROLE; POLY(3,4-ETHYLENEDIOXYTHIOPHENE); MICROELECTRODES; STIMULATION; STABILITY; COMPOSITE; SCAFFOLDS; HYDROGELS; DELIVERY;

D O I：

10.1016/j.drudis.2013.07.022

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

During a single decade of research, evidence has emerged that glial scar formation around the electrotissue interface drives neural loss and increases the signal impedance of the electrodes, compromising the efficiency of the stimulating systems. Studies with conducting polymers (CPs) as electrode coatings have shown enhanced tissue integration and electrode performance in situ through biochemical and physicomechanical functionalisation. In this review, recent findings on CP modifications are provided in the context of neurospecific biomaterials, shedding light on the valuable impact of multifunctionalised strategies for biomedical applications.

引用

页码：88 / 94

页数：7

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