A turn-on fluorescent probe for detection of hydrogen sulfide in aqueous solution and living cells

被引：27

作者：

Zhu, Dongjian ^{[1
,2
]}

Xue, Lin ^{[1
]}

Li, Guoping ^{[1
]}

Che, Yanke ^{[1
]}

Jiang, Hua ^{[1
,3
]}

机构：

[1] Chinese Acad Sci, Beijing Natl Lab Mol Sci, CAS Key Lab Photochem, Inst Chem, Beijing 100190, Peoples R China

[2] Univ Chinese Acad Sci, Beijing 100190, Peoples R China

[3] Beijing Normal Univ, Coll Chem, Beijing 100875, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2014年 / 1卷 / 05期

基金：

中国国家自然科学基金;

关键词：

RAPID DETECTION; HYPOXIC CELLS; REDOX CYCLE; SE-BODIPY; H2S; RECOGNITION; MARKERS; GAS;

D O I：

10.1039/c4qo00048j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report the design and synthesis of a turn-on fluorescence probe FD-NO2 for H2S, utilizing H2S selective reduction of the nitro group. FD-NO2 displays good water solubility, negligible background fluorescence, high sensitivity, and high selectivity for H2S over other anions, reactive sulfur, oxygen, and nitrogen species. Further confocal imaging experiments demonstrate that FD-NO2 is capable of detecting H2S in living cells.

引用

页码：501 / 505

页数：5

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