Prospective study of Hepatitis E Virus infection among pregnant women in France

被引:46
|
作者
Renou, Christophe [1 ]
Gobert, Vincent [2 ]
Locher, Christophe [2 ]
Moumen, Abdelouahab [3 ]
Timbely, Oumar [3 ]
Savary, Janine [4 ]
Roque-Afonso, Anne-Marie [4 ,5 ,6 ]
机构
[1] Ctr Hosp Hyeres, Hop Jour, F-83407 Hyeres, France
[2] Ctr Hosp Meaux, F-77104 Meaux, France
[3] Ctr Hosp Meaux, F-77104 Meaux, France
[4] Hop Paul Brousse, AP HP, F-94804 Villejuif, France
[5] Univ Paris 11, UMR S 785, F-94804 Villejuif, France
[6] INSERM U785, F-94804 Villejuif, France
来源
VIROLOGY JOURNAL | 2014年 / 11卷
关键词
HEV; Seroprevalence; Pregnancy; France; BLOOD-DONORS; PREVALENCE; ANTIBODIES;
D O I
10.1186/1743-422X-11-68
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Background: Hepatitis E Virus (HEV) infection has a poor prognosis among pregnant women from high endemic countries. HEV-prevalence and incidence among pregnant women is unknown in high-income countries such as France. This prospective study was conducted to assess HEV infection in this setting. Findings: An overall HEV prevalence of 7.74% was observed among 315 pregnant women. Seroprevalence was higher in south than in north of France (29.3% vs. 3.6%, p < 0.0001), and women with detectable IgG were older. No IgG seroconversion or IgM detection were observed during pregnancy. Conclusions: Data suggest that HEV infection is a rare occurrence during pregnancy even in regions of western countries with high seroprevalence rates.
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页数:3
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