Prospective study of Hepatitis E Virus infection among pregnant women in France

被引：46

作者：

Renou, Christophe ^{[1
]}

Gobert, Vincent ^{[2
]}

Locher, Christophe ^{[2
]}

Moumen, Abdelouahab ^{[3
]}

Timbely, Oumar ^{[3
]}

Savary, Janine ^{[4
]}

Roque-Afonso, Anne-Marie ^{[4
,5
,6
]}

机构：

[1] Ctr Hosp Hyeres, Hop Jour, F-83407 Hyeres, France

[2] Ctr Hosp Meaux, F-77104 Meaux, France

[3] Ctr Hosp Meaux, F-77104 Meaux, France

[4] Hop Paul Brousse, AP HP, F-94804 Villejuif, France

[5] Univ Paris 11, UMR S 785, F-94804 Villejuif, France

[6] INSERM U785, F-94804 Villejuif, France

来源：

VIROLOGY JOURNAL | 2014年 / 11卷

关键词：

HEV; Seroprevalence; Pregnancy; France; BLOOD-DONORS; PREVALENCE; ANTIBODIES;

D O I：

10.1186/1743-422X-11-68

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Background: Hepatitis E Virus (HEV) infection has a poor prognosis among pregnant women from high endemic countries. HEV-prevalence and incidence among pregnant women is unknown in high-income countries such as France. This prospective study was conducted to assess HEV infection in this setting. Findings: An overall HEV prevalence of 7.74% was observed among 315 pregnant women. Seroprevalence was higher in south than in north of France (29.3% vs. 3.6%, p < 0.0001), and women with detectable IgG were older. No IgG seroconversion or IgM detection were observed during pregnancy. Conclusions: Data suggest that HEV infection is a rare occurrence during pregnancy even in regions of western countries with high seroprevalence rates.

引用

页数：3

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