Atorvastatin-Induced Necrotizing Myopathy and its Response to Combination Therapy

被引：4

作者：

Boppana, Sri Harsha ^{[1
]}

Syed, Hasan A. ^{[2
]}

Antwi-Amoabeng, Daniel ^{[2
]}

Reddy, Prahlad ^{[3
]}

Gullapalli, Nageshwara

机构：

[1] Univ Nevada, Internal Med, Reno, NV 89557 USA

[2] Univ Nevada, Internal Med, Reno Sch Med, Reno, NV 89557 USA

[3] Arthrit Consultants, Rheumatol, Reno, NV USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2021年 / 13卷 / 01期

关键词：

atorvastatin; myopathy; ANTI-HMGCR ANTIBODIES; AUTOIMMUNE MYOPATHY; HISTORY; STATINS;

D O I：

10.7759/cureus.12957

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Atorvastatin is the most commonly used stalin medication to decrease cholesterol levels and prevent atherosclerosis. Myopathy is a reported side effect of atorvastatin which can happen even after more than six months after starting the medication. The side effect on the muscle tissue can range from simple reversible myalgia to respiratory muscle compromise. Here we present a 46-year-old male who presented with myopathy after taking atorvastatin for two years. Biopsy proved immune-mediated necrotizing myopathy which responded to a combination of Rituximab and intravenous immunoglobulin therapy.

引用

页数：4

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