One-Pot Multicomponent Synthesis of Imidazole Rings in Acidic Ionic Liquids: A Review

被引：6

作者：

Eze, Cosmas Chinweike ^{[1
]}

Ezeokonkwo, Mercy Amarachi ^{[2
]}

Ezema, Benjamin Ebere ^{[2
]}

Onoabedje, Abraham Efeturi ^{[2
]}

Ibeanu, Fidelia Ngozika ^{[1
]}

Ugwu, David Izuchukwu ^{[2
]}

Onyeyilim, Leonard Ebuka ^{[2
]}

Ezugwu, James Anayochwkwu ^{[2
]}

机构：

[1] Univ Nigeria, Sch Gen Studies, Nat Sci Unit, Nsukka 410001, Enugu State, Nigeria

[2] Univ Nigeria, Dept Pure & Ind Chem, Nsukka 410001, Enugu State, Nigeria

来源：

MINI-REVIEWS IN ORGANIC CHEMISTRY | 2020年 / 17卷 / 08期

关键词：

Environmental sustainability; imidazole; ionic liquids; multicomponent; one-pot synthesis; organic synthesis; SOLVENT-FREE SYNTHESIS; CATALYZED ONE-POT; CELLULOSE SULFURIC-ACID; 1,2,4,5-TETRASUBSTITUTED IMIDAZOLES; TETRASUBSTITUTED IMIDAZOLES; SUBSTITUTED IMIDAZOLES; EFFICIENT CATALYST; REUSABLE CATALYST; TRICHLOROISOCYANURIC ACID; HIGHLY EFFICIENT;

D O I：

10.2174/1570193X17666200226110645

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The design of the environmentally friendly approach to the synthesis of biologically important compounds without compromising the yield has been the focus of many chemists in recent years. The development of the one-pot synthesis of heterocycles in the presence of Ionic Liquids (ILs), used as both environmental media and catalysts, is efficient and environmentally sustainable. This review highlights the one-pot synthesis of imidazoles in acidic ILs in the past decade. Some reviews have been conducted on imidazoles, such as their pharmacological importance. Hence, we decided to focus on their synthesis in acidic ionic liquids, which the authors are not aware of any published literature.

引用

页码：975 / 990

页数：16

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