Efficient synthesis of imidazole and pyrimidine derivatives

被引：2
|
作者：
Kolomoitsev, Oleksii O. [1 ]
Gladkov, Eugene S. [1 ,2 ]
Kotlyar, Volodymyr M. [1 ]
Pedan, Polina I. [3 ]
Onipko, Oleksandr V. [3 ]
Buravov, Oleksandr V. [3 ]
Chebanov, Valentyn A. [1 ,2 ]
机构：
[1] Kharkov Natl Univ, 4 Svobody Sq, UA-61022 Kharkiv, Ukraine
[2] Natl Acad Sci Ukraine, Inst Single Crystals, State Sci Inst, 60 Nauky Ave, UA-61072 Kharkiv, Ukraine
[3] Enamine Ltd, 67 Chervonotkatska St, UA-02660 Kiev, Ukraine
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2020年 / 56卷 / 10期
关键词：
alpha-aminoamidine; 1-chloropropan-2-one; 3-(diethylamino)prop-2-enal; heterocycle; imidazole; pyrimidine; ELIMINATION; INHIBITORS; AMIDINES; ANALOGS;
D O I：
10.1007/s10593-020-02818-x
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A convenient and affordable synthetic pathway for obtaining new alpha-aminoamidines starting from aminonitriles is proposed. The alpha-aminoamidines obtained can be applied as substrates for further transformations and synthesis of imidazole- and pyrimidine-containing building blocks.
引用
收藏
页码：1329 / 1334
页数：6
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