Identification of a Modulatory Site of Action for the Volatile Anesthetic Isoflurane in TREK1 Tandem Pore Potassium Channels

被引:0
|
作者
Riegelhaupt, Paul M. [1 ]
Woll, Kellie A. [2 ]
Joseph, Thomas T. [2 ]
Vaidya, Kiran A. [1 ]
Nimigean, Crina M. [1 ]
Eckenhoff, Roderic G. [2 ]
机构
[1] Weill Cornell Med, New York, NY USA
[2] Univ Penn, Philadelphia, PA 19104 USA
关键词
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
2409-Pos
引用
收藏
页码:487A / 488A
页数:2
相关论文
共 34 条
  • [31] Inhibition of two-pore domain potassium channels TASK-1 by endothelin-1 is Rhokinase dependent with Ser393 as the predominant phosphorylation site
    Seyler, C.
    Duthil-Straub, E.
    Zitron, E.
    Scholz, E. P.
    Thomas, D.
    Gierten, J.
    Karle, C. A.
    Fink, R. H. A.
    CARDIOVASCULAR RESEARCH, 2010, 87 : S59 - S59
  • [32] Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformation reveals details of site 1 toxin and local anesthetic binding
    Scheib, Holger
    McLay, Iain
    Guex, Nicolas
    Clare, Jeff J.
    Blaney, Frank E.
    Dale, Tim J.
    Tate, Simon N.
    Robertson, Graeme M.
    JOURNAL OF MOLECULAR MODELING, 2006, 12 (06) : 813 - 822
  • [33] Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformation reveals details of site 1 toxin and local anesthetic binding
    Holger Scheib
    Iain McLay
    Nicolas Guex
    Jeff J. Clare
    Frank E. Blaney
    Tim J. Dale
    Simon N. Tate
    Graeme M. Robertson
    Journal of Molecular Modeling, 2006, 12 : 813 - 822
  • [34] Tandem pore domain potassium channels TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 modulate effector functions of T lymphocytes: a novel therapeutic target for T-cell mediated autoimmune diseases
    Meuth, S. G.
    Bittner, S.
    Simon, O.
    Kleinschnitz, C.
    Budde, T.
    Wiendl, H.
    MULTIPLE SCLEROSIS, 2007, 13 : S34 - S34