Identification of a Modulatory Site of Action for the Volatile Anesthetic Isoflurane in TREK1 Tandem Pore Potassium Channels

被引：0
|
作者：
Riegelhaupt, Paul M. [1 ]
Woll, Kellie A. [2 ]
Joseph, Thomas T. [2 ]
Vaidya, Kiran A. [1 ]
Nimigean, Crina M. [1 ]
Eckenhoff, Roderic G. [2 ]
机构：
[1] Weill Cornell Med, New York, NY USA
[2] Univ Penn, Philadelphia, PA 19104 USA
来源：
BIOPHYSICAL JOURNAL | 2018年 / 114卷 / 03期
关键词：
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
2409-Pos
引用
收藏
页码：487A / 488A
页数：2
相关论文
共 34 条
  • [1] IDENTIFICATION OF A MODULATORY SITE OF ACTION FOR THE VOLATILE ANESTHETIC ISOFLURANE IN TREK1 TANDEM PORE POTASSIUM CHANNELS
    Riegelhaupt, Paul M.
    Woll, Kellie
    Joseph, Thomas T.
    Vaidya, Kiran A.
    Nimigean, Crina M.
    Eckenhoff, Roderic G.
    ANESTHESIA AND ANALGESIA, 2018, 126 (04): : 48 - 48
  • [2] Engineering an off-switch for background TREK1 potassium channels
    Riel, Elena B.
    Goldberg, Louis
    Riegelhaupt, Paul M.
    BIOPHYSICAL JOURNAL, 2024, 123 (03) : 29A - 29A
  • [3] Influence of the N Terminus on the Biophysical Properties and Pharmacology of TREK1 Potassium Channels
    Veale, Emma L.
    Al-Moubarak, Ehab
    Bajaria, Naina
    Omoto, Kiyoyuki
    Cao, Lishuang
    Tucker, Stephen J.
    Stevens, Edward B.
    Mathie, Alistair
    MOLECULAR PHARMACOLOGY, 2014, 85 (05) : 671 - 681
  • [4] Convergence of Multiple Stimuli to a Single Gate in TREK1 and TRAAK Potassium Channels
    Choveau, Frank S.
    Ben Soussia, Ismail
    Bichet, Delphine
    Franck, Chatelain C.
    Feliciangeli, Sylvain
    Lesage, Florian
    FRONTIERS IN PHARMACOLOGY, 2021, 12
  • [5] Enhancement of Current through Trek1 Two Pore Domain Channels by Flufenamic Acid
    Al-Moubarak, Ehab
    Mathie, Alistair
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 748A - 748A
  • [6] Covalent Modification of a Volatile Anesthetic Regulatory Site Activates TASK-3 (KCNK9) Tandem-Pore Potassium Channels
    Conway, Kevin E.
    Cotten, Joseph F.
    MOLECULAR PHARMACOLOGY, 2012, 81 (03) : 393 - 400
  • [7] The structural movement of the TM4 segment during pore gating in TREK1 channels
    Schulz, F.
    Rapedius, M.
    Tucker, S. J.
    Baukrowitz, T.
    ACTA PHYSIOLOGICA, 2017, 219 : 80 - 80
  • [8] TREK1 potassium channels on brain endothelial cells regulate immune cell migration into the CNS
    Bittner, S.
    ACTA PHYSIOLOGICA, 2014, 210 : 8 - 8
  • [9] Local anesthetic inhibition of baseline potassium channels with two pore domains in tandem
    Kindler, CH
    Yost, CS
    Gray, AT
    ANESTHESIOLOGY, 1999, 90 (04) : 1092 - 1102
  • [10] Expression of TASK1 and TREK1, two-pore domain K channels, in human myometrium.
    Bai, XL
    Baker, PN
    Taggart, MJ
    Fyfe, GK
    JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, 2005, 12 (02) : 208A - 208A
1234