Chromone and chromanone glucosides from Hypericum sikokumontanum and their anti-Helicobacter pylori activities

被引：40

作者：

Tanaka, Naonobu ^{[1
]}

Kashiwada, Yoshiki ^{[1
]}

Nakano, Tatsuro ^{[1
]}

Shibata, Hirofumi ^{[1
]}

Higuchi, Tomihiko ^{[1
]}

Sekiya, Michiko ^{[2
]}

Ikeshiro, Yasumasa ^{[2
]}

Takaishi, Yoshihisa ^{[1
]}

机构：

[1] Univ Tokushima, Grad Sch Pharmaceut Sci, Tokushima 7708505, Japan

[2] Niigata Univ Pharm & Appl Life Sci, Fac Pharmaceut Sci, Niigata 9568683, Japan

来源：

PHYTOCHEMISTRY | 2009年 / 70卷 / 01期

关键词：

Hypericum sikokumontanum; Guttiferae; Chromone glucoside; Chromanone glucoside; Helicobacter pylori; Cytotoxicity; C-13; NMR; PHENOLIC-COMPOUNDS; LATHYRUS-ODORATUS; XANTHONES; GLYCOSIDES; DERIVATIVES; FLAVONOIDS; CHINENSE; SPECTROSCOPY; CONSTITUENTS;

D O I：

10.1016/j.phytochem.2008.11.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chromone glucosides, takanechromones A-C (1, 2 and S) and chromanone glucosides, named takanechromanones A and B (3 and 4), were isolated from the methanolic extracts of Hypericum sikokumontanum together with 27 known compounds. Their structures were established based on spectroscopic evidence. The isolated compounds and some chromone derivatives were assayed for antimicrobial activity against Helicobacter pylori and cytotoxicity against human cancer cell lines. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：141 / 146

页数：6

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