Use of mesoporous silica as theophylline adsorbent in drug delivery system

被引：0
|
作者：
Moritz, Michal [1 ]
机构：
[1] Politechn Poznanska, Wydzial Technol Chem, Inst Chem & Elektrochem Tech, Zaklad Chem Ogolnej & Analit, PL-60965 Poznan, Poland
来源：
PRZEMYSL CHEMICZNY | 2013年 / 92卷 / 11期
关键词：
SBA-15; RELEASE; CARRIER;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Mesoporous SiO2 was produced by decompn. of Si(OEt)(4), modified with NH2(CH2)(2)Si(OEt)(3) and used for adsorption of theophylline from Me2CHOH/CHCl3 soln. at room temp. The adsorbed theophylline was then released to water or aq. HCl soln. (concn. 0.1 mol/L) at 37 +/- 2 degrees C. The modification of the SiO2 adsorbent resulted in an increase in its adsorption capacity by 60% and a decrease in the theophylline releasing rate.
引用
收藏
页码：2093 / 2096
页数：4
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