Expression and significance of RRBP1 in esophageal carcinoma

被引：13

作者：

Wang, Liang ^{[1
]}

Wang, Ming ^{[2
]}

Zhang, Mingyun ^{[1
]}

Li, Xingde ^{[1
]}

Zhu, Zhongcheng ^{[1
]}

Wang, Haiyan ^{[2
]}

机构：

[1] Cangzhou Cent Hosp, Dept Endoscop Profess, 16 Xinhua West Rd, Cangzhou 061001, Peoples R China

[2] Cangzhou Cent Hosp, Dept Radiat Therapy, Cangzhou, Peoples R China

来源：

CANCER MANAGEMENT AND RESEARCH | 2018年 / 10卷

关键词：

RRBP1; prognosis; esophageal carcinoma; survival analysis; PREDICTS POOR-PROGNOSIS; RIBOSOME-BINDING PROTEIN-1; SQUAMOUS-CELL CARCINOMA; ENDOPLASMIC-RETICULUM; COLORECTAL-CANCER; TUMOR; OVEREXPRESSION; PROGRESSION; SURVIVAL; RECEPTOR;

D O I：

10.2147/CMAR.S158013

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Objective: This study was to investigate the expression and clinical significance of RRBP1 in esophageal carcinoma. Materials and methods: RRBP1 expression was detected in 120 esophageal carcinoma and matched adjacent normal tissues, and the relationship of RRBP1 with clinicopathological characteristics and prognosis was analyzed. Results: RRBP1 was highly expressed in esophageal carcinoma tissues compared with matched adjacent normal tissues (P< 0.05). Moreover, RRBP1 expression was associated with T stage, lymph node metastasis, and TNM stage in esophageal carcinoma (P< 0.05). Survival analysis revealed that RRBP1, T stage, lymph node metastasis, and TNM stage were significantly associated with patients' prognosis. Conclusion: RRBP1 is highly expressed in esophageal carcinoma and can serve as a potential biomarker to predict patients' prognosis.

引用

页码：1243 / 1249

页数：7

共 50 条

[31] Prognostic Significance of NBS1 and Snail Expression in Esophageal Squamous Cell Carcinoma
Kuang-Tai Kuo
Teh-Ying Chou
Han-Shui Hsu
Wen-Liang Chen
Liang-Shun Wang
[J]. Annals of Surgical Oncology, 2012, 19 : 549 - 557
[32] RRBP1在结直肠癌组织中的表达及临床意义
杨帆
张匠
毛英
[J]. 保健医学研究与实践, 2019, 16 (06) : 44 - 47
[33] PINCH expression and its significance in esophageal squamous cell carcinoma
Zhu, Zhenlong
Yang, Yanhong
Zhang, Yu
Wang, Zhengmin
Cui, Dongsheng
Zhang, Jinting
Wang, Mingwei
Sun, Xiao-Feng
[J]. DISEASE MARKERS, 2008, 25 (02) : 75 - 80
[34] Expression and clinical significance of Apollon in esophageal squamous cell carcinoma
Li, Rong
Chen, Bo-lin
Zhou, Yan-wu
Guo, Ren-wei
Shuai, Meng-ting
Zeng, Jun-xian
Leng, Ai-min
[J]. MOLECULAR MEDICINE REPORTS, 2016, 14 (03) : 1933 - 1940
[35] Expression and significance of CFTR in human esophageal squamous cell carcinoma
Matsumoto, Yoshihisa
Shiozaki, Atsushi
Kudou, Michihiro
Shimizu, Hiroki
Kosuga, Toshiyuki
Arita, Tomohiro
Yamamoto, Yusuke
Konishi, Hirotaka
Morimura, Ryo
Kuriu, Yoshiaki
Ikoma, Hisashi
Kubota, Takeshi
Fujiwara, Hitoshi
Okamoto, Kazuma
Otsuji, Eigo
[J]. CANCER SCIENCE, 2021, 112 : 788 - 788
[36] Clinical Significance of Cyclophilin A Expression in Esophageal Squamous Cell Carcinoma
Feng, Ming-Xiang
Li, Jing-Pei
Wang, Hao
Shen, Ya-Xing
Tan, Li-Jie
Wang, Qun
Wang, Yu-Qi
[J]. GENETIC TESTING AND MOLECULAR BIOMARKERS, 2015, 19 (04) : 182 - 186
[37] Clinical significance of EGFR and EGFRvIII expression in human esophageal carcinoma
Duan, Xiaoyi
Zhou, Suna
Zhang, Mingxin
Wang, Peng
Zhang, Jia
Wang, Jiansheng
[J]. PAKISTAN JOURNAL OF MEDICAL SCIENCES, 2011, 27 (03) : 490 - 495
[38] EXPRESSION AND CLINICAL SIGNIFICANCE OF NPRA IN ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Wang, J.
Zhao, Z.
Fang, H.
Tangsakar, E.
Zhang, J.
[J]. ANNALS OF ONCOLOGY, 2012, 23 : 248 - 248
[39] Expression and clinical significance of retinoid X receptor α in esophageal carcinoma
Ren, Hong-Yue
Guo, Yi-He
Yang, Li-Min
Dai, Tai-Jian
Lin, Ming-Zhu
Yu, Le
Zhu, Qi-Gan
Meng, Jia-Rong
[J]. ANNALS OF DIAGNOSTIC PATHOLOGY, 2018, 34 : 110 - 115
[40] Prognostic significance of dysadherin expression in esophageal squamous cell carcinoma
Shimada, Y
Hashimoto, Y
Kan, T
Kawamura, J
Okumura, T
Soma, T
Kondo, K
Teratani, N
Watanabe, G
Ino, Y
Sakamoto, M
Hirohashi, S
Imamura, M
[J]. ONCOLOGY, 2004, 67 (01) : 73 - 80

← 1 2 3 4 5 →