The role of systemic and targeted therapies in brain metastases

被引：5
|
作者：
Franceschi, Enrico [1 ]
Bartolotti, Marco [1 ]
Poggi, Rosalba [1 ]
Di Battista, Monica [1 ]
Palleschi, Dario [1 ]
Brandes, Alba A. [1 ]
机构：
[1] Azienda USL Bologna, Bellaria Maggiore Hosp, Dept Med Oncol, I-40139 Bologna, Italy
来源：
EXPERT REVIEW OF ANTICANCER THERAPY | 2014年 / 14卷 / 01期
关键词：
BRAF V600E melanoma; brain metastases; EGFR mutations; HER2 breast cancer; target therapy; CELL LUNG-CANCER; LAPATINIB PLUS CAPECITABINE; PHASE-II TRIAL; TYROSINE KINASE INHIBITORS; EARLY BREAST-CANCER; RADIATION-THERAPY; OPEN-LABEL; INTRACRANIAL METASTASES; ADJUVANT TRASTUZUMAB; CEREBRAL METASTASES;
D O I：
10.1586/14737140.2014.856760
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
For many years, brain metastases (BMs) have been considered as the final stage of a disease course and engendered skepticism about the efficacy of treatments. Local treatments, mainly, whole-brain radiotherapy have been the standard of care, whereas chemotherapy has been considered of limited efficacy due to the potential role of blood-brain barrier.
引用
收藏
页码：93 / 103
页数：11
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