N-[2-(azepan-1-yl)-9-isopropyl-9H-purin-6-yl]-4-methoxybenzylamine

被引：8
|
作者：
Trávnícek, Z
Zatloukal, M
机构：
[1] Palacky Univ, Fac Sci, Dept Inorgan Chem, CZ-77147 Olomouc, Czech Republic
[2] Palacky Univ, Lab Growth Regulators, CZ-78371 Olomouc, Czech Republic
[3] Palacky Univ, AS CR, Inst Expt Bot, CZ-78371 Olomouc, Czech Republic
来源：
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2004年 / 60卷
关键词：
D O I：
10.1107/S1600536804010207
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The title compound, C22H30N6O, is a potent inhibitor of estrogen sulfotransferase which catalyses the transfer of a sulfuryl group from 3'-phosphoadenosine 5'-phosphosulfate to estrogen and estrogen-like compounds. The pyrimidine plane forms dihedral angles of 81.53 (4) and 2.99 (4)degrees with the benzene and imidazole rings, respectively. The crystal structure is stabilized by N-H...N hydrogen bonds connecting two adjacent molecules, thus forming centrosymmetric dimers, the N...N distance being 3.0403 (16) Angstrom.
引用
收藏
页码：O924 / O926
页数：3
相关论文
共 50 条
  • [41] 2-(6-amino-7H-purin-7-yl)-1-phenylethanone
    Buehler, Stefanie
    Schollmeyer, Dieter
    Hauser, Dominik
    Laufer, Stefan
    Peifer, Christian
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O4646 - U4473
  • [42] N-(9-Oxo-9H-thioxanthen-2-yl) acrylamide as a Versatile Photoinitiator for Photopolymerization
    Wu, Qingqing
    Yang, Guiqin
    Guo, Jingdong
    Li, Fushao
    Deng, Mingsen
    CHEMISTRYSELECT, 2022, 7 (44):
  • [43] NOVEL REARRANGEMENT OF N-(9H-CARBAZOL-9-YL)ARYLAMINYL RADICALS
    LEARDINI, R
    LUCARINI, M
    NANNI, A
    NANNI, D
    PEDULLI, GF
    TUNDO, A
    ZANARDI, G
    JOURNAL OF ORGANIC CHEMISTRY, 1993, 58 (09): : 2419 - 2423
  • [44] N,N-Dimethyl-4-[(E)-2-(3,6,7-tribromo-9-butyl-9H-carbazol-2-yl)ethenyl]aniline
    Kumar, Sushil
    Thomas, K. R. Justin
    Ng, Seik Weng
    Tiekink, Edward R. T.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O1121 - +
  • [45] (S)-N-(N-(((2R, 3S, 4R, 5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)sulfamoyl)-5-oxopyrrolidine-2-carboxamide
    Khaybullin, Ravil N.
    Liang, Xiao
    Qi, Xin
    MOLBANK, 2015, (02)
  • [46] 2-(9,9-Diethyl-9H-fluoren-2-yl)-1-benzofuran
    Huang, Ping-Hsin
    Lin, Kai-Ling
    Wen, Yuh-Sheng
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O743 - U2890
  • [47] N-(2-(1H-Indol-3-yl)ethyl)-2-(2-fluoro[1,1′-biphenyl]-4-yl)propanamide
    Manolov, Stanimir
    Ivanov, Iliyan
    Bojilov, Dimitar
    MOLBANK, 2021, 2021 (01) : 1 - 4
  • [48] CYCLIZATIONS OF SUBSTITUTED N-(PURIN-6-YL)-2-AMINOETHANOL SYSTEM
    LIRA, EP
    JOURNAL OF ORGANIC CHEMISTRY, 1968, 33 (08): : 3355 - &
  • [49] Synthesis of base substituted 2-hydroxy-3-(purin-9-yl)-propanoic acids and 4-(purin-9-yl)-3-butenoic acids
    Doláková, P
    Masojídková, M
    Holy, A
    NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2003, 22 (12): : 2145 - 2160
  • [50] N-(4a-morpholino-2,3,4,4a,9,9a-hexahydro-1H-xanthen-9-yl)phenylamine
    Bhaskaran, S
    Selvanayagam, S
    Velmurugan, D
    Ravikumar, K
    Anniyappan, M
    Muralidharan, D
    Perumal, PT
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2003, 59 : O1301 - O1303
12345