N-[2-(azepan-1-yl)-9-isopropyl-9H-purin-6-yl]-4-methoxybenzylamine

被引：8
|
作者：
Trávnícek, Z
Zatloukal, M
机构：
[1] Palacky Univ, Fac Sci, Dept Inorgan Chem, CZ-77147 Olomouc, Czech Republic
[2] Palacky Univ, Lab Growth Regulators, CZ-78371 Olomouc, Czech Republic
[3] Palacky Univ, AS CR, Inst Expt Bot, CZ-78371 Olomouc, Czech Republic
来源：
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2004年 / 60卷
关键词：
D O I：
10.1107/S1600536804010207
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The title compound, C22H30N6O, is a potent inhibitor of estrogen sulfotransferase which catalyses the transfer of a sulfuryl group from 3'-phosphoadenosine 5'-phosphosulfate to estrogen and estrogen-like compounds. The pyrimidine plane forms dihedral angles of 81.53 (4) and 2.99 (4)degrees with the benzene and imidazole rings, respectively. The crystal structure is stabilized by N-H...N hydrogen bonds connecting two adjacent molecules, thus forming centrosymmetric dimers, the N...N distance being 3.0403 (16) Angstrom.
引用
收藏
页码：O924 / O926
页数：3
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