The interaction of bacterial pathogens with platelets

被引：364
|
作者：
Fitzgerald, J. Ross [1 ]
Foster, Timothy J.
Cox, Dermot
机构：
[1] Univ Dublin Trinity Coll, Dept Microbiol, Moyne Inst Prevent Med, Dublin 2, Ireland
[2] Univ Edinburgh, Ctr Infect Dis, New Royal Infirm, Edinburgh EH16 4SB, Midlothian, Scotland
[3] Royal Coll Surgeons Ireland, Sch Pharm, Dublin 2, Ireland
来源：
NATURE REVIEWS MICROBIOLOGY | 2006年 / 4卷 / 06期
关键词：
D O I：
10.1038/nrmicro1425
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
In recent years, the frequency of serious cardiovascular infections such as endocarditis has increased, particularly in association with nosocomially acquired antibiotic-resistant pathogens. Growing evidence suggests a crucial role for the interaction of bacteria with human platelets in the pathogenesis of cardiovascular infections. Here, we review the nature of the interactions between platelets and bacteria, and the role of these interactions in the pathogenesis of endocarditis and other cardiovascular diseases.
引用
收藏
页码：445 / 457
页数：13
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