Hashimoto's Encephalopathy Presenting with Smoldering Limbic Encephalitis

被引：5

作者：

Nagano, Masahiro ^{[1
]}

Kobayashi, Katsuya ^{[1
]}

Yamada-Otani, Mayumi ^{[1
]}

Kuzuya, Akira ^{[1
]}

Matsumoto, Riki ^{[1
]}

Oita, Jiro ^{[2
]}

Yoneda, Makoto ^{[3
]}

Ikeda, Akio ^{[4
]}

Takahashi, Ryosuke ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Med, Dept Neurol, Kyoto, Japan

[2] Shimizu Hosp, Dept Neurol, Shizuoka, Japan

[3] Fukui Prefectural Univ, Fac Nursing & Social Welf Sci, Eiheiji, Fukui, Japan

[4] Kyoto Univ, Grad Sch Med, Dept Epilepsy Movement Disorders & Physiol, Kyoto, Japan

来源：

INTERNAL MEDICINE | 2019年 / 58卷 / 08期

关键词：

Hashimoto's encephalopathy; FDG-PET; video EEG; autoimmune limbic encephalitis; anti-NAE antibody; STEROID-RESPONSIVE ENCEPHALOPATHY; FDG-PET; ANTIBODIES; FREQUENT;

D O I：

10.2169/internalmedicine.1289-18

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hashimoto's encephalopathy (HE) is a steroid-responsive autoimmune encephalopathy associated with Hashimoto thyroiditis. We herein report a case of HE manifesting "smoldering" limbic encephalitis with persisting symptoms and abnormalities on examinations. Although our patient experienced partial clinical remission after treatment, hippocampal hypermetabolism on [F-18] fluorodeoxyglucose positron emission tomography (FDG-PET) and subclinical seizures on video electroencephalography persisted. Hypermetabolism on FDG-PET was improved by additional prednisolone therapy. Thus, as with other autoimmune limbic encephalitis cases, HE can take a course of "smoldering" encephalitis. FDG-PET and electroencephalogram findings can reflect the disease activity degree in such patients, although with certain neurophysiological and biochemical distinctions.

引用

页码：1167 / 1172

页数：6

共 50 条

[21] Hashimoto's Encephalopathy Presenting with Progressive Cerebellar Ataxia
Algahtani, Hussein A.
Fatani, Anmar N.
Shirah, Bader H.
Algahtani, Raghad H.
NEUROSCIENCES, 2019, 24 (04) : 315 - 319
[22] Hashimoto's encephalopathy presenting as an acute medical emergency
Sommerfield, AJ
Stimson, R
Campbell, IW
SCOTTISH MEDICAL JOURNAL, 2004, 49 (04) : 155 - 156
[23] Hashimoto's disease presenting as encephalitis in a young woman
Zambrana, JL
Fuentes, F
Rosa, F
Velasco, MJ
AMERICAN JOURNAL OF MEDICINE, 2002, 112 (02): : 163 - 164
[24] Hashimoto's encephalopathy presenting with progressive cerebellar ataxia
Nakagawa, H.
Yoneda, M.
Fujii, A.
Kinomoto, K.
Kuriyama, M.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2007, 78 (02): : 196 - 197
[25] Anti-NMDAR encephalitis misdiagnosed as Hashimoto's encephalopathy
Mirabelli-Badenier, M.
Biancheri, R.
Morana, G.
Fornarino, S.
Siri, L.
Celle, M. E.
Veneselli, E.
Vincent, A.
Gaggero, R.
Mancardi, M. M.
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY, 2014, 18 (01) : 72 - 74
[26] Hashimoto's Encephalopathy Mimicking Viral Encephalitis: A Case Report
Yu, Miaomiao
Yang, Yu
Ma, Xianyi
Xie, Yinyin
Sun, Ningning
Meng, Hongmei
FRONTIERS IN NEUROSCIENCE, 2020, 14
[27] Hashimoto encephalopathy (autoimmune encephalitis) - Comment
Seshadri, P
JCR-JOURNAL OF CLINICAL RHEUMATOLOGY, 2004, 10 (06) : 343 - 343
[28] Neurosyphilis presenting as limbic encephalitis
Shrimpton, Matthew
Malhotra, Abhishek
BMJ CASE REPORTS, 2023, 16 (12)
[29] Neurosyphilis Presenting as Limbic Encephalitis
Petrin, Myriam
Verreault, Steve
NEUROLOGY, 2011, 76 (09) : A430 - A431
[30] Neurosarcoidosis presenting as limbic encephalitis
Mahatoo, Ashmanie
Gadani, Anvi
Zhang, Yan
Tremblay, Matthew
NEUROLOGY, 2020, 94 (15)

← 1 2 3 4 5 →