Microwave-assisted one-pot synthesis of trisubstituted imidazoles on solid support

被引:0
|
作者
Xu, Y [1 ]
Wan, LF [1 ]
Salehi, H [1 ]
Deng, W [1 ]
Guo, QX [1 ]
机构
[1] Univ Sci & Technol China, Dept Chem, Hefei 230026, Peoples R China
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暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A solvent-free microwave-assisted synthesis of trisubstituted imidazoles is reported. The imidazoles are produced by the condensation of alpha-hydroxyketone with an aldehyde over silica gel or alumina impregnated with ammonium acetate as the solid support in short time with good yields. An air oxidation mechanism is proposed, and this clean air oxidation considerably reduces the cost of imidazole synthesis.
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页码:1613 / 1618
页数:6
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