Serotonergic pathways in the Drosophila larval enteric nervous system

被引：31

作者：

Schoofs, Andreas ^{[1
]}

Hueckesfeld, Sebastian ^{[1
]}

Surendran, Sandya ^{[1
]}

Pankratz, Michael J. ^{[1
]}

机构：

[1] Univ Bonn, LIMES Inst, Dept Mol Brain Physiol, D-53115 Bonn, Germany

来源：

JOURNAL OF INSECT PHYSIOLOGY | 2014年 / 69卷

关键词：

Serotonin; Enteric nervous system; Post-ingestive motility; Drosophila; Foregut; 3RD INSTAR LARVAE; FEEDING-BEHAVIOR; NEURONS; MELANOGASTER; ANATOMY; CHANNELRHODOPSIN-2; ACTIVATION; FOREGUT; CIRCUIT; PATTERN;

D O I：

10.1016/j.jinsphys.2014.05.022

中图分类号：

Q96 [昆虫学];

学科分类号：

摘要：

The enteric nervous system is critical for coordinating diverse feeding-related behaviors and metabolism. We have characterized a cluster of four serotonergic neurons in Drosophila larval brain: cell bodies are located in the subesophageal ganglion (SOG) whose neuronal processes project into the enteric nervous system. Electrophysiological, calcium imaging and behavioral analyses indicate a functional role of these neurons in modulating foregut motility. We suggest that the axonal projections of this serotonergic cluster may be part of a brain-gut neural pathway that is functionally analogous to the vertebrate vagus nerve. (C) 2014 The Authors. Published by Elsevier Ltd.

引用

页码：118 / 125

页数：8

共 50 条

[41] Understanding the enteric nervous system
Boeckxstaens, GE
[J]. UPDATE GASTROENTEROLOGY 2004: NEW DEVELOPMENTS IN THE MANAGEMENT OF BENIGN GASTROINTESTINAL DISORDERS, 2004, : 69 - 69
[42] THE ENTERIC NERVOUS-SYSTEM
COSTA, M
BROOKES, SJH
[J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 1994, 89 (08): : S129 - S137
[43] The Aging Enteric Nervous System
Nguyen, Tinh Thi
Baumann, Peter
Tuescher, Oliver
Schick, Sandra
Endres, Kristina
[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (11)
[44] Extending the enteric nervous system
Sbarbati, Andrea
Osculati, Francesco
[J]. BIOMEDICINE & PHARMACOTHERAPY, 2007, 61 (07) : 377 - 382
[45] Enterotoxins and the enteric nervous system
Farthing, MJG
[J]. RECENT ADVANCES IN THE PATHOGENESIS OF GASTROINTESTINAL BACTERIAL INFECTIONS, 1998, : 191 - 203
[46] Neurogenesis in the enteric nervous system
Metzger, M.
[J]. ARCHIVES ITALIENNES DE BIOLOGIE, 2010, 148 (02): : 73 - 83
[47] Immunology and enteric nervous system
Frieling, T
[J]. DIGESTIVE PHYSIOLOGY IN PIGS, 1997, (88): : 234 - 238
[48] The human enteric nervous system
Schemann, M
Neunlist, M
[J]. NEUROGASTROENTEROLOGY AND MOTILITY, 2004, 16 : 55 - 59
[49] Development of the enteric nervous system
Gershon, MD
[J]. FASEB JOURNAL, 2002, 16 (04): : A28 - A28
[50] Inflammation and the enteric nervous system
Wood, JD
[J]. PROCEEDINGS OF THE 11TH INTERNATIONAL CONFERENCE ON ULCER RESEARCH, 2003, : 181 - 187

← 1 2 3 4 5 →