Sarcopenia and hypertrophy: A role for insulin-like growth factor-1 in aged muscle?

被引：49

作者：

Hameed, M

Harridge, SDR

Goldspink, G

机构：

[1] UCL, Royal Free & Univ Coll Med Sch, Dept Physiol, London NW3 2PF, England

[2] UCL, Royal Free & Univ Coll Med Sch, Dept Anat & Dev Biol, London NW3 2PF, England

来源：

EXERCISE AND SPORT SCIENCES REVIEWS | 2002年 / 30卷 / 01期

关键词：

muscle; strength; growth factors; aging; protein synthesis;

D O I：

10.1097/00003677-200201000-00004

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Sarcopenia is the loss of muscle mass associated with the aging process. Although systemic or circulating growth hormone and insulin-like growth factor-1 levels fall as we age, this is likely to be of lesser importance in regard to muscle mass than the rule of locally produced insulin-like growth factor-Is generated in the muscle in response to exercise.

引用

页码：15 / 19

页数：5

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