Cysteine 98 in CYP3A4 contributes to conformational integrity required for p450 interaction with CYP reductase

被引：0
|
作者：
Wen, Bo
Huang, Christine S.
Rodrigues, A. David
Lampe, Jed N.
Atkins, William M.
Nelson, Sidney D.
机构：
[1] Bristol Myers Squibb, Princeton, NJ USA
[2] Univ Washington, Seattle, WA 98195 USA
来源：
DRUG METABOLISM REVIEWS | 2006年 / 38卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
391
引用
收藏
页码：254 / 255
页数：2
相关论文
共 50 条
  • [21] Effect of Dihydromyricetin on Cytochrome P450 Isoforms CYP1A2, CYP2C9 and CYP3A4 in Rats
    Huang, Yi
    Xu, Zhi-sheng
    Ye, Qiang
    LATIN AMERICAN JOURNAL OF PHARMACY, 2013, 32 (10): : 1570 - 1574
  • [22] Comparison of CYP3A4 and CYP3A5: The Effects of Cytochrome b5 and NADPH-cytochrome P450 Reductase on Testosterone Hydroxylation Activities
    Lee, Su-Jun
    Gldstein, Joyce A.
    DRUG METABOLISM AND PHARMACOKINETICS, 2012, 27 (06) : 663 - 667
  • [23] Creation of polarized cells coexpressing CYP3A4, NADPH cytochrome P450 reductase and MDR1/P-glycoprotein
    Brimer, C
    Dalton, JT
    Zhu, ZX
    Schuetz, J
    Yasuda, K
    Vanin, E
    Relling, MV
    Lu, Y
    Schuetz, EG
    PHARMACEUTICAL RESEARCH, 2000, 17 (07) : 803 - 810
  • [24] Creation of Polarized Cells Coexpressing CYP3A4, NADPH Cytochrome P450 Reductase and MDR1/P-glycoprotein
    Cynthia Brimer
    James T. Dalton
    Zixin Zhu
    John Schuetz
    Kazuto Yasuda
    Elio Vanin
    Mary V. Relling
    Yi Lu
    Erin G. Schuetz
    Pharmaceutical Research, 2000, 17 : 803 - 810
  • [25] A Useful Model Capable of Predicting the Clearance of Cytochrome P450 3A4 (CYP3A4) Substrates in Humans: Validity of CYP3A4 Transgenic Mice Lacking Their Own Cyp3a Enzymes
    Mitsui, Tetsuya
    Nemoto, Takayuki
    Miyake, Taiji
    Nagao, Shunsuke
    Ogawa, Kotaro
    Kato, Motohiro
    Ishigai, Masaki
    Yamada, Hideyuki
    DRUG METABOLISM AND DISPOSITION, 2014, 42 (09) : 1540 - 1547
  • [26] Effect of the combination of chlorzoxazone and dehydroepiandrosterone in CYP3A4 and CYP2E1 isoenzymes of the cytochrome P450 system
    Lopez, Maria
    Santos, Lizette
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 251
  • [27] Modulation of P-glycoprotein and cytochrome P450(CYP3A4) by extracts of Turnera diffusa leaves
    Sinha, S. D.
    Harle, U. N.
    Gaikwad, N. J.
    INDIAN JOURNAL OF PHARMACOLOGY, 2008, 40 : 93 - 93
  • [28] Development of Caco-2 cells co-expressing CYP3A4 and NADPHcytochrome P450 reductase using a human artificial chromosome for the prediction of intestinal extraction ratio of CYP3A4 substrates
    Takenaka, Toru
    Kazuki, Kanako
    Harada, Naomoto
    Kuze, Jiro
    Chiba, Masato
    Iwao, Takahiro
    Matsunaga, Tamihide
    Abe, Satoshi
    Oshimura, Mitsuo
    Kazuki, Yasuhiro
    DRUG METABOLISM AND PHARMACOKINETICS, 2017, 32 (01) : 61 - 68
  • [29] Changes in CYP19A1 and CYP3A4 Activities Due to Population Genetic Variations in Human P450 Oxidoreductase
    Parween, Shaheena
    Udhane, Sameer S.
    Kagawa, Norio
    Pandey, Amit V.
    HORMONE RESEARCH IN PAEDIATRICS, 2018, 90 : 77 - 77
  • [30] Clozapine and levomepromazine induce the cytochrome P450 isoenzyme CYP3A4, but not CYP1A1/2, in human hepatocytes
    Danek, P.
    Basinska-Ziobron, A.
    Daniel, W. A.
    Wojcikowski, J.
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2017, 27 : S927 - S927
12345