Sarcomatoid carcinoma of urinary bladder: Immunohistochemical study of an uncommon case

被引：6
|
作者：
Cappello, F [1 ]
Aragona, F [1 ]
Serretta, V [1 ]
Randazzo, G [1 ]
Melloni, D [1 ]
机构：
[1] Univ Palermo, Inst Pathol Anat, Palermo, Italy
来源：
UROLOGIA INTERNATIONALIS | 2002年 / 69卷 / 02期
关键词：
sarcomatoid carcinoma; urinary bladder tumors; human pancytokeratin; AE1/AE3; cytokeratins;
D O I：
10.1159/000065564
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
A case of sarcomatoid carcinoma of the bladder is reported herein. Immunohistochemical staining with human pancytokeratin antibody was negative, while vimentin staining was strongly positive, suggesting a diagnosis of sarcoma of the bladder. Further immunohistochemical analysis revealed positivity for AE1/AE3 cyto-keratins, permitting a correct diagnosis of sarcomatoid carcinoma of the bladder. It can be difficult to distinguish between sarcomatoid carcinoma, undifferentiated carcinoma and sarcoma, particularly if the biopsy specimens are of small size. In rare cases, sarcomatoid tumors may express epithelial markers different from those revealed by human pancytokeratin staining. Copyright (C) 2002 S. Karger AG, Basel.
引用
收藏
页码：141 / 144
页数：4
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