Application of nanosecond-pulsed dielectric barrier discharge for biomedical treatment of topographically non-uniform surfaces

被引:108
|
作者
Ayan, H. [1 ]
Staack, D. [1 ]
Fridman, G. [2 ]
Gutsol, A. [3 ]
Mukhin, Y. [1 ]
Starikovskii, A. [1 ]
Fridman, A. [1 ]
Friedman, G. [4 ]
机构
[1] Drexel Univ, Coll Engn, Dept Mech Engn & Mech, Philadelphia, PA 19104 USA
[2] Drexel Univ, Sch Biomed Engn Sci & Hlth Syst, Philadelphia, PA 19104 USA
[3] Chevron Energy Technol Co, Richmond, CA 94802 USA
[4] Drexel Univ, Coll Engn, Dept Elect & Comp Engn, Philadelphia, PA 19104 USA
关键词
PLASMA; STERILIZATION;
D O I
10.1088/0022-3727/42/12/125202
中图分类号
O59 [应用物理学];
学科分类号
摘要
Antimicrobial effectiveness of a nanosecond-pulsed dielectric barrier discharge (DBD) was investigated and compared with that of a microsecond-pulsed DBD. Experiments were conducted on the Escherichia coli bacteria covering a topographically non-uniform agar surface acting as one of the DBD electrodes. They reveal that the nanosecond-pulsed DBD can inactivate bacteria in recessed areas whereas the microsecond-pulsed and conventional DBDs fail to do so. Charged species (electrons and ions) appear to play the major role in the bacteria inactivation with the nanosecond-pulsed DBD. Moreover, the nanosecond-pulsed DBD kills bacteria significantly faster than its microsecond-pulsed counterpart.
引用
收藏
页数:5
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