Application of nanosecond-pulsed dielectric barrier discharge for biomedical treatment of topographically non-uniform surfaces

被引：108

作者：

Ayan, H. ^{[1
]}

Staack, D. ^{[1
]}

Fridman, G. ^{[2
]}

Gutsol, A. ^{[3
]}

Mukhin, Y. ^{[1
]}

Starikovskii, A. ^{[1
]}

Fridman, A. ^{[1
]}

Friedman, G. ^{[4
]}

机构：

[1] Drexel Univ, Coll Engn, Dept Mech Engn & Mech, Philadelphia, PA 19104 USA

[2] Drexel Univ, Sch Biomed Engn Sci & Hlth Syst, Philadelphia, PA 19104 USA

[3] Chevron Energy Technol Co, Richmond, CA 94802 USA

[4] Drexel Univ, Coll Engn, Dept Elect & Comp Engn, Philadelphia, PA 19104 USA

来源：

JOURNAL OF PHYSICS D-APPLIED PHYSICS | 2009年 / 42卷 / 12期

关键词：

PLASMA; STERILIZATION;

D O I：

10.1088/0022-3727/42/12/125202

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

Antimicrobial effectiveness of a nanosecond-pulsed dielectric barrier discharge (DBD) was investigated and compared with that of a microsecond-pulsed DBD. Experiments were conducted on the Escherichia coli bacteria covering a topographically non-uniform agar surface acting as one of the DBD electrodes. They reveal that the nanosecond-pulsed DBD can inactivate bacteria in recessed areas whereas the microsecond-pulsed and conventional DBDs fail to do so. Charged species (electrons and ions) appear to play the major role in the bacteria inactivation with the nanosecond-pulsed DBD. Moreover, the nanosecond-pulsed DBD kills bacteria significantly faster than its microsecond-pulsed counterpart.

引用

页数：5

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