Confidence maps and confidence intervals for near infrared images in breast cancer

被引:8
|
作者
Tosteson, TD
Pogue, BW
Demidenko, E
McBride, TO
Paulsen, KD
机构
[1] Dartmouth Med Sch, Lebanon, NH 03756 USA
[2] Dartmouth Coll, Thayer Sch Engn, Hanover, NH 03755 USA
关键词
confidence maps; confidence intervals; image reconstruction; near infrared spectroscopic tomography;
D O I
10.1109/42.819328
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
This paper extends basic concepts of statistical hypothesis testing and confidence intervals to images generated by a new procedure for near infrared spectroscopic tomography being developed for use in breast cancer diagnosis. By estimating the covariance matrix of the pixels of an image from data used in the image reconstruction process, confidence maps for statistical tests on individual pixels and confidence intervals for entire images are displayed as an aid to research and clinical personnel interpreting possibly noisy images. The methods are applied to simulated and phantom-based images.
引用
收藏
页码:1188 / 1193
页数:6
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