RNA interference pinpoints regulators of cell size and the cell cycle

被引:4
|
作者
Cully, Megan J.
Leevers, Sally J.
机构
[1] Canc Res UK London Res Inst, Growth Regulat Lab, London WC2A 3PX, England
[2] Canc Res UK London Res Inst, Signal Transduct Lab, London WC2A 3PX, England
关键词
D O I
10.1186/gb-2006-7-5-219
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Cell-based genome-wide RNA interference screens are being used to address an increasingly broad spectrum of biological questions. In one recent screen, Drosophila cell cultures treated with double-stranded RNA were analyzed by flow cytometry, providing a wealth of new information and identifying 488 regulators of the cell cycle, cell size, and cell death.
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页数:3
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