Acupuncture in the prophylactic treatment of migraine without aura: A comparison with flunarizine

被引:89
|
作者
Allais, G
De Lorenzo, C
Quirico, PE
Airola, G
Tolardo, G
Mana, O
Benedetto, C
机构
[1] Univ Turin, Dept Gynecol & Obstet, Womans Headache Ctr, I-10126 Turin, Italy
[2] Ctr Study Nat & Phys Therapies, Turin, Italy
来源
HEADACHE | 2002年 / 42卷 / 09期
关键词
acupuncture; flunarizine; migraine; prophylaxis; randomized controlled trial;
D O I
10.1046/j.1526-4610.2002.02203.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objectives.-In a randomized controlled trial extending over 6 months, we evaluated the effectiveness of acupuncture versus flunarizine in the prophylactic treatment of migraine without aura. Methods.-One hundred sixty women with migraines were randomly assigned to acupuncture treatment (group A, n = 80) or to an oral therapy with flunarizine (group F, n = 80). In group A, acupuncture was carried out in weekly sessions for the first 2 months and then once a month for the next 4 months. The same acupoints were used at each treatment: LR3 Taichong, SP6 Sanyinjiao, ST36 Zusanli, CV12 Zhongwan, LI4 Hegu, PC6 Neiguan, GB20 Fengchi, GB14 Yangbai, EX-HN5 Taiyang, GV20 Baihui. In group F, 10 mg flunarizine were given daily for the first 2 months and then for 20 days per month for the next 4 months. Results.-The frequency of attacks and use of symptomatic drugs significantly decreased during treatment in both groups. The number of attacks after 2 and 4 months of therapy was significantly lower in group A than in group F, and analgesic consumption was significantly lower in group A at 2 months of treatment. At 6 months no such differences existed between the two treatment groups. Pain intensity was significantly reduced only by acupuncture treatment. Side effects were significantly less frequent in group A. Conclusions.-Acupuncture proved to be adequate for migraine prophylaxis. Relative to flunarizine, acupuncture treatment exhibited greater effectiveness in the first months of therapy and superior tolerability.
引用
收藏
页码:855 / 861
页数:7
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