Protective effect of lutein on ischemia-reperfusion injury in rat small intestine

被引：7
|
作者：
Ogura, Wakako
Itagaki, Shirou
Kurokawa, Toshirnitsu
Noda, Toshihiro
Hirano, Takeshi
Mizuno, Satoshi
Iseki, Ken
机构：
[1] Hokkaido Univ, Dept Clin Pharmaceut & Therapeut, Grad Sch Pharmaceut Sci, Kita Ku, Sapporo, Hokkaido 0600812, Japan
[2] Kemin Foods Asia, Minato Ku, Tokyo 1050001, Japan
来源：
BIOLOGICAL & PHARMACEUTICAL BULLETIN | 2006年 / 29卷 / 08期
关键词：
lutein; ischemia-reperfusion; carotenoid; antioxidant;
D O I：
10.1248/bpb.29.1764
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Lutein is a carotenoid and it has antioxidant effects. Lutein may have a protective effect on ischemia reperfusion (I/R) injury induced by free radical species. However, little is known about the protective effect of lutein on I/R injury in vivo. The present study was undertaken to clarify the protective effects of lutein on I/R injuries in the rat small intestine. Administration of lutein before intestinal I/R attenuated the damage to villi and deciduation of enterocytes and suppressed the increase in lipid peroxide.
引用
收藏
页码：1764 / 1766
页数：3
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