Hematoma volume as the major determinant of outcomes after intracerebral hemorrhage

被引:106
|
作者
LoPresti, Melissa A. [1 ]
Bruce, Samuel S. [1 ]
Camacho, Elvis [1 ]
Kunchala, Sudkir [1 ]
Dubois, Byron G. [1 ]
Bruce, Eliza [1 ]
Appelboom, Geoff [1 ]
Connolly, E. Sander, Jr. [1 ]
机构
[1] Columbia Univ, Dept Neurosurg, Med Ctr, Cerebrovasc Lab, New York, NY 10027 USA
关键词
Hematoma volume; Intracerebral hemorrhage; Stroke; Hematoma expansion; Outcomes; Predictors; ACTIVATED FACTOR-VII; PROTHROMBIN COMPLEX CONCENTRATE; COMMUNITY STROKE PROJECT; FRESH-FROZEN PLASMA; INTRAVENTRICULAR HEMORRHAGE; SUBARACHNOID HEMORRHAGE; MULTIVARIATE-ANALYSIS; 30-DAY MORTALITY; RISK-FACTORS; BLOOD-FLOW;
D O I
10.1016/j.jns.2014.06.057
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Intracerebral hemorrhage (ICH) is a leading cause of morbidity and mortality, greatly linked to hematoma volume. Understanding the characteristics and size of hematoma is integral to evaluating severity and prognosis after ICH. Examination of the literature suggests that markers for hematoma size vary, but the key range between 20-30 mL is most widely used as the cut-off for classification of hematoma volume. The role of hematoma volume in episodes of hematoma expansion and re-bleeding further impact outcomes, with increased growth associated with larger hematoma volume. Additionally, many commonly used predictors of ICH outcomes are directly related to hematoma volume, implicating it as an important variable when determining outcomes. In conclusion, hematoma volume is likely the most significant determinant of outcomes in intracerebral hemorrhage. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码:3 / 7
页数:5
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