Synthesis of 3-acetyl-2-amino-4-pyridone

被引：8
|
作者：
Dorokhov, VA
Komkov, AV
Sakharov, AM
Bogdanov, VS
机构：
[1] N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 117913 Moscow
来源：
RUSSIAN CHEMICAL BULLETIN | 1996年 / 45卷 / 01期
关键词：
diacetylketene aminal; diphenylboron chelates; dimethylformamide dimethylacetal; intramolecular cyclization; 3-acetyl-2-amino-4-pyridone;
D O I：
10.1007/BF01433755
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A method for synthesizing 3-acetyl-2-amino-4-pyridone has been suggested. The synthesis involves the condensation of dimethylformamide dimethylacetal at the NH2 group of diphenylboron chelate diacetylketene aminal followed by its intramolecular cyclization under the action of NaOMe in MeOH.
引用
收藏
页码：168 / 170
页数：3
相关论文
共 50 条
  • [11] Ethyl 5-acetyl-2-amino-4-methylthiophene-3-carboxylate
    Akkurt, Mehmet
    Yildirim, Sema Oeztuerk
    Asiri, Abdullah Mohamed
    McKee, Vickie
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1084 - U2230
  • [12] TAUTOMERIC EQUILIBRIUM CONSTANTS FOR 3-AMINO- AND 3-NITRO-4-PYRIDONE
    JONES, RA
    RONEY, BD
    JOURNAL OF THE CHEMICAL SOCIETY B-PHYSICAL ORGANIC, 1967, (01): : 84 - &
  • [13] ACTIVATED NITRILES IN HETEROCYCLIC SYNTHESIS .3. SYNTHESIS OF N-AMINO-2-PYRIDONE, PYRANOPYRAZOLE AND THIAZOLOPYRIDINE DERIVATIVES
    ELMOGHAYAR, MRH
    ELAGAMEY, AGA
    NASR, MYAS
    SALLAM, MMM
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1984, 21 (06) : 1885 - 1887
  • [14] STUDIES ON AMINO-ACID DERIVATIVES .4. SYNTHESIS OF 3-AMINO-2(1H)-PYRIDONE DERIVATIVES USING 4-ETHOXYMETHYLENE-2-PHENYL-5-OXAZOLONE
    CHIBA, T
    TAKAHASHI, T
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1985, 33 (07) : 2731 - 2734
  • [15] Various approaches to the use of 3-acetyl-2-amino-4-hydroxy-1,3-pentadienecarbonitrile in heterocyclic synthesis
    Dorokhov, VA
    Azarevich, OG
    Bogdanov, VS
    Vasilev, LS
    RUSSIAN CHEMICAL BULLETIN, 1997, 46 (01) : 122 - 125
  • [16] Various approaches to the use of 3-acetyl-2-amino-4-hydroxy-1,3-pentadienecarbonitrile in heterocyclic synthesis
    V. A. Dorokhov
    O. G. Azarevich
    V. S. Bogdanov
    L. S. Vasil'ev
    Russian Chemical Bulletin, 1997, 46 : 122 - 125
  • [17] ACTIVATED NITRILES IN HETEROCYCLIC SYNTHESIS .2. SYNTHESIS OF N-AMINO-2-PYRIDONE DERIVATIVES
    ELMOGHAYAR, MRH
    ELAGAMEY, AGA
    ABED, NM
    IBRAHIM, MKA
    ANALES DE QUIMICA SERIE C-QUIMICA ORGANICA Y BIOQUIMICA, 1985, 81 (03): : 236 - 238
  • [18] Synthesis of novel dyes derived from 1-ethyl-3-cyano-6-hydroxy-4-methyl-5-amino-2-pyridone
    Song, HF
    Chen, KC
    Tian, H
    DYES AND PIGMENTS, 2002, 53 (03) : 257 - 262
  • [19] PYRIDONE DERIVATIVES OF 3-AMINO-2H-AZIRINES AND CYCLOPROPRENONES
    CHALOUPKA, S
    HEIMGARTNER, H
    CHIMIA, 1978, 32 (12) : 468 - 470
  • [20] Synthesis of methyl-4-anilino-3-amino/amino-acetyl benzoates as anti-filarial agents
    Beg, MSJ
    Singh, BN
    Raj, P
    ASIAN JOURNAL OF CHEMISTRY, 2003, 15 (01) : 519 - 522
12345