Saponins from the roots of Panax notoginseng

被引：104
|
作者：
Ma, WG
Mizutani, M
Malterud, KE
Lu, SL
Ducrey, B
Tahara, S [1 ]
机构：
[1] Hokkaido Univ, Fac Agr, Dept Appl Biosci, Kita Ku, Sapporo, Hokkaido 0608589, Japan
[2] Japan Sci & Technol Corp, CREST, Kawaguchi, Saitama 3320012, Japan
[3] Univ Oslo, Dept Pharmacognosy, Inst Pharm, N-0316 Oslo, Norway
[4] State Owned Kunming Chinese Herbs Factory, Kunming 650228, Yunnan, Peoples R China
[5] Debio Rech Pharmaceut SA, CH-1920 Martigny, Switzerland
来源：
PHYTOCHEMISTRY | 1999年 / 52卷 / 06期
关键词：
Panax notoginseng; Ariliaceae; ethnic medicinal plant; ginsenoside; notoginsenoside; bioactive saponin;
D O I：
10.1016/S0031-9422(99)00364-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The glycosidic fraction from the dried roots of Panax notoginseng (Burk.) F.H. Chen exhibited an inhibitory effect on zoospore motility of Aphanomyces cochlioides. Further study on this fraction afforded fourteen dammarane-type saponins. Their structures were determined on the basis of spectroscopic and chemical methods. Eleven were known compounds, and the three new ones were 3-O-[beta-D-glucopyranosyl (1 --> 6)-beta-D-glucopyranosyl]20-O-beta-D-glucopyranosyl 3 beta, 12 beta, 20 (S)-trihydroxydammar-24-ene, 3-O-beta-D-glucopyranosyl 20-O-[alpha-L-arabinopyranosyl (1 --> 2)-beta-D-glucopyranosyl] 3 beta, 12 beta, 20 (S)-trihydroxydammar-24-ene and 6-O-beta-D-glucopyranosyl 20-O-beta-D-glucopyranosyl 3 beta, 6 alpha, 12 beta, 20 (S), 25-pentahydroxydammar-23-ene, respectively. Each saponin displayed good inhibitory effects on zoospore motility. (C) 1999 Elsevier Science Ltd. All rights reserved.
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页码：1133 / 1139
页数：7
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