A facile chemoselective deprotection of the p-methoxybenzyl group

被引：27
|
作者：
Yu, WS [1 ]
Su, M [1 ]
Gao, XB [1 ]
Yang, ZQ [1 ]
Jin, ZD [1 ]
机构：
[1] Univ Iowa, Coll Pharm, Div Med & Nat Prod Chem, Iowa City, IA 52242 USA
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 21期
关键词：
p-methoxybenzyl group; thioglycosides; orthoganol deprotection;
D O I：
10.1016/S0040-4039(00)00574-8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The p-methoxybenzyl (PMB) group can be chemoselectively cleaved at low temperature in the presence of SnCl4 and thiophenol. This method is especially useful in the cases where oxidative reagents such as DDQ and CAN need to be avoided. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：4015 / 4017
页数：3
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