Comparison of Retinal Nerve Fiber Layer Thickness Measured by Cirrus HD and Stratus Optical Coherence Tomography

被引:173
|
作者
Sung, Kyung Rim [1 ]
Kim, Dong Yoon [1 ]
Park, Sung Bae [1 ]
Kook, Michael S. [1 ]
机构
[1] Univ Ulsan, Coll Med, Dept Ophthalmol, Asan Med Ctr, Seoul 138736, South Korea
关键词
SCANNING LASER POLARIMETRY; EARLY GLAUCOMA; OCULAR HYPERTENSION; MACULAR THICKNESS; EYES; REPRODUCIBILITY; DISK; OCT; CLASSIFIERS; PROGRESSION;
D O I
10.1016/j.ophtha.2008.12.045
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To study the relationship between retinal nerve fiber layer (RNFL) thickness measured by time domain (Stratus) and spectral domain (Cirrus HD) optical coherence tomography (OCT). Design: Cross-sectional study. Participants: Sixty healthy participants, 48 glaucoma suspects, and 55 subjects with glaucoma. Methods: Participants were imaged by a single trained operator using the Stratus OCT (fast RNFL scan mode) and Cirrus HD-OCT (optic disc cube mode) at the same visit. Main Outcome Measures: The RNFL thickness as measured by the Stratus OCT (fast RNFL scan mode) and Cirrus HD-OCT (optic disc cube mode) was compared (paired t test). The relationship between RNFL thickness measurements of the 2 OCTs were evaluated using a Pearson correlation analysis. The presence of abnormal classification, as determined by using an internal normative data base in each machine was compared (chi-square test). The sensitivity and specificity of normative classification of 2 OCT measurements were calculated. Results: Average RNFL thickness as determined by the 2 OCT machines was correlated (r = 0.94; P<0.001), but was significantly different with the 2 machines (Stratus, 98.0 mu m, standard deviation [SD] 18.0; Cirrus, 85.6 mu m, SD 14.6; P<0.001). The Cirrus HD-OCT classified a significantly higher percentage of eyes as abnormal (Stratus, 12.9%; Cirrus, 23.3%; P<0.001) in average RNFL thickness. Cirrus OCT demonstrated higher sensitivity and specificity (63.6% and 100%) than Stratus OCT (40.0% and 96.7%) in normative classification of average RNFL thickness. Conclusions: There were significant differences in RNFL thickness and normative classification as determined by Stratus OCT and Cirrus HD-OCT despite an excellent correlation of RNFL thickness measurement. Overall sensitivity and specificity were higher with Cirrus OCT. These findings are particularly relevant when an individual undergoes longitudinal follow-up with different OCTs. Financial Disclosure(s): The authors have no commercial or proprietary interest in any of the materials discussed in this article. Ophthalmology 2009,116:1264-1270 (C) 2009 by the American Academy of Ophthalmology.
引用
收藏
页码:1264 / 1270
页数:7
相关论文
共 50 条
  • [11] Retinal nerve fiber layer thickness in normal children measured with optical coherence tomography
    Salchow, DJ
    Oleynikov, YS
    Chiang, MF
    Kennedy-Salchow, SE
    Langton, K
    Tsai, JC
    Al-Aswad, LA
    OPHTHALMOLOGY, 2006, 113 (05) : 786 - 791
  • [12] Peripapillary retinal nerve fibre layer thickness in highly myopic Caucasians as measured by Stratus optical coherence tomography
    Vemon, S. A.
    Rotchford, A. P.
    Negi, A.
    Ryatt, S.
    Tattersal, C.
    BRITISH JOURNAL OF OPHTHALMOLOGY, 2008, 92 (08) : 1076 - 1080
  • [13] A Comparison of Retinal Nerve Fiber Layer Thickness Measured Using Five Different Optical Coherence Tomography Devices
    Lee, Youn Gon
    Hwang, Young Hoon
    JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY, 2018, 59 (03): : 261 - 267
  • [14] Effects of posterior capsular opacification on the evaluation of retinal nerve fiber layer as measured by stratus optical coherence tomography
    Kara, Necip
    Altinkaynak, Hasan
    Yuksel, Kemal
    Kurt, Tugba
    Demirok, Ahmet
    CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE, 2012, 47 (02): : 176 - 180
  • [15] Comparison of Glaucoma Diagnostic Capabilities of Cirrus HD and Stratus Optical Coherence Tomography
    Park, Seong Bae
    Sung, Kyung Rim
    Kang, Sung Yong
    Kim, Kyung Ri
    Kook, Michael S.
    ARCHIVES OF OPHTHALMOLOGY, 2009, 127 (12) : 1603 - 1609
  • [16] Evaluation of heredity as a determinant of retinal nerve fiber layer thickness as measured by optical coherence tomography
    Hougaard, JL
    Kessel, L
    Sander, B
    Kyvik, KO
    Sorensen, TIA
    Larsen, M
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2003, 44 (07) : 3011 - 3016
  • [17] Evaluation of the effect of aging on retinal nerve fiber layer thickness measured by optical coherence tomography
    Kanamori, A
    Escano, MFT
    Eno, A
    Nakamura, M
    Maeda, H
    Seya, R
    Ishibashi, K
    Negi, A
    OPHTHALMOLOGICA, 2003, 217 (04) : 273 - 278
  • [18] Evaluation of the glaucomatous damage on retinal nerve fiber layer thickness measured by optical coherence tomography
    Kanamori, A
    Nakamura, M
    Escano, MFT
    Seya, R
    Maeda, H
    Negi, A
    AMERICAN JOURNAL OF OPHTHALMOLOGY, 2003, 135 (04) : 513 - 520
  • [19] Analysis of the retinal nerve fiber layer texture related to the thickness measured by optical coherence tomography
    Odstrcilik, J.
    Kolar, R.
    Tornow, R. P.
    Budai, A.
    Jan, J.
    Mackova, P.
    Vodakova, M.
    COMPUTATIONAL VISION AND MEDICAL IMAGE PROCESSING IV, 2014, : 105 - 110
  • [20] Retinal nerve fiber layer thickness in a healthy Turkish population measured by optical coherence tomography
    Cubuk, Mehmet
    Sahinoglu-Keskek, Nedime
    Keskek, Sakir Ozgur
    ANNALS OF SAUDI MEDICINE, 2016, 36 (06) : 409 - 413