Palladium-catalyzed esterification-hydroarylation reactions of 2-alkynylbenzaldehydes with aryl iodides in methanol

被引：52
|
作者：
Wei, LL
Wei, LM
Pan, WB
Wu, MJ [1 ]
机构：
[1] Kaohsiung Med Univ, Fac Med & Appl Chem, Kaohsiung 807, Taiwan
[2] Fooyin Univ, Kaohsiung 831, Taiwan
[3] Kaohsiung Med Univ, Grad Inst Pharmaceut Sci, Kaohsiung 807, Taiwan
来源：
SYNLETT | 2004年 / 09期
关键词：
palladium; coupling; esterification-hydroarylation; 2-alkynylbenzaldehydes;
D O I：
10.1055/s-2004-829056
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reaction of 2-alkynylbenzaldehydes with aryl iodides in the presence of Pd(PPh3)(4) and K2CO3 in refluxing methanol for 24 hours gave the dehydrogenation-addition products, methyl 2(2,2-disubstituted-vinyl)benzoates in modest yields; together with the cyclization products, 3-methoxy-1-inonosubstituted-methylene-3-hydroisobenzofurans in 3-18% yields.
引用
收藏
页码：1497 / 1502
页数：6
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