Formulation of Dry Emulsion for Topical Applications

被引:10
|
作者
Gallarate, Marina [1 ]
Mittone, Elena [1 ]
Carlotti, M. Eugenia [1 ]
Trotta, Michele [1 ]
Piccerelle, Philippe [2 ]
机构
[1] Univ Turin, Dipartimento Sci & Tecnol Farm, I-10125 Turin, Italy
[2] Univ Aix Marseille 2, Pharm Galen Lab, Fac Pharm, F-13284 Marseille 07, France
关键词
Dry emulsions; freeze-drying; Vitis vinifera; PROTEIN/LACTOSE/SOYBEAN OIL-EMULSIONS; DOSAGE FORM; STABILITY; PHOTOSTABILITY; OPTIMIZATION; DELIVERY; TIME;
D O I
10.1080/01932690802643998
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Dry emulsions were investigated for their possible use in cosmetic and pharmaceutical fields and an extract of Vitis vinifera leaves was obtained and characterized in terms of quality and quantitative levels, which can be introduced in a selected dry emulsion formulation. Several pre-dry emulsions were prepared, six of which were chosen as a consequence of their satisfying physico-chemical and over-time stability characteristics. They were successively freeze-dried and reconstituted after optimising the reconstitution modalities and characterized by optical microscopy, granulometric and thermal analysis, FTIR analysis, rheology, and texture studies. The best formulation was chosen to introduce Vitis vinifera dry extract prepared by percolation: a fair increase in anthocians stability was noted over time in dry emulsions as compared with classic emulsions.
引用
收藏
页码:823 / 833
页数:11
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