Formulation of Dry Emulsion for Topical Applications

被引:10
|
作者
Gallarate, Marina [1 ]
Mittone, Elena [1 ]
Carlotti, M. Eugenia [1 ]
Trotta, Michele [1 ]
Piccerelle, Philippe [2 ]
机构
[1] Univ Turin, Dipartimento Sci & Tecnol Farm, I-10125 Turin, Italy
[2] Univ Aix Marseille 2, Pharm Galen Lab, Fac Pharm, F-13284 Marseille 07, France
关键词
Dry emulsions; freeze-drying; Vitis vinifera; PROTEIN/LACTOSE/SOYBEAN OIL-EMULSIONS; DOSAGE FORM; STABILITY; PHOTOSTABILITY; OPTIMIZATION; DELIVERY; TIME;
D O I
10.1080/01932690802643998
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Dry emulsions were investigated for their possible use in cosmetic and pharmaceutical fields and an extract of Vitis vinifera leaves was obtained and characterized in terms of quality and quantitative levels, which can be introduced in a selected dry emulsion formulation. Several pre-dry emulsions were prepared, six of which were chosen as a consequence of their satisfying physico-chemical and over-time stability characteristics. They were successively freeze-dried and reconstituted after optimising the reconstitution modalities and characterized by optical microscopy, granulometric and thermal analysis, FTIR analysis, rheology, and texture studies. The best formulation was chosen to introduce Vitis vinifera dry extract prepared by percolation: a fair increase in anthocians stability was noted over time in dry emulsions as compared with classic emulsions.
引用
收藏
页码:823 / 833
页数:11
相关论文
共 50 条
  • [1] Formulation and characterisation of artemether-loaded nano-emulsion for topical applications
    van Jaarsveld, Esmari
    du Plessis, Jeanetta
    du Preez, Jan L.
    Shahzad, Yasser
    Gerber, Minja
    JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2022, 73
  • [2] Formulation and characterization of a Helianthus annuus - alkyl polyglucoside emulsion cream for topical applications
    Banerjee, Kaushita
    Thiagarajan, Narayanaswamy
    Thiagarajan, Padma
    JOURNAL OF COSMETIC DERMATOLOGY, 2019, 18 (02) : 628 - 637
  • [3] Topical formulation of Boswellia nano emulsion in psoriasis mouse model
    Fereidouni, Mohammad
    Shadi, Mehri
    Mahmoudian, Reihaneh Alsadat
    Ghasemi, Javad
    Mahzoon, Mohammad Erfan
    Faraji, Saba
    Mansouri, Atena
    ARCHIVES OF DERMATOLOGICAL RESEARCH, 2024, 317 (01)
  • [4] FORMULATION AND STABILITY EVALUATION OF BAUHINIA VARIEGATA EXTRACT TOPICAL EMULSION
    Mohsin, Sabeeh
    Akhtar, Naveed
    ACTA POLONIAE PHARMACEUTICA, 2017, 74 (03): : 945 - 954
  • [5] Formulation and Characterization of Novel Dry Suspension and Dry Emulsion of 20(S)-Protopanaxadiol
    Zhang, Liying
    Xu, Congcong
    Mao, Jingjing
    Wang, Weiwei
    Han, Han
    Pu, Yiqiong
    Zhang, Tong
    AAPS PHARMSCITECH, 2019, 20 (07)
  • [6] Formulation and Characterization of Novel Dry Suspension and Dry Emulsion of 20(S)-Protopanaxadiol
    Liying Zhang
    Congcong Xu
    Jingjing Mao
    Weiwei Wang
    Han Han
    Yiqiong Pu
    Tong Zhang
    AAPS PharmSciTech, 20
  • [7] Formulation studies of microemulsions for topical applications of acyclovir
    Peira, E.
    Chirio, D.
    Carlotti, M. E.
    Spagnolo, R.
    Trotta, M.
    JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2009, 19 (03) : 191 - 196
  • [8] RECENT PROGRESS IN FORMULATION OF VEHICLES FOR TOPICAL APPLICATIONS
    HADGRAFT, JW
    BRITISH JOURNAL OF DERMATOLOGY, 1972, 87 (04) : 386 - &
  • [9] An enteric-coated dry emulsion formulation for oral insulin delivery
    Toorisaka, E
    Hashida, M
    Kamiya, N
    Ono, H
    Kokazu, Y
    Goto, M
    JOURNAL OF CONTROLLED RELEASE, 2005, 107 (01) : 91 - 96
  • [10] Formulation of a lyophilized dry emulsion tablet for the delivery of poorly soluble drugs
    Corveleyn, S
    Remon, JP
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1998, 166 (01) : 65 - 74