Prognostic and Predictive Factors of Ebola Virus Disease Outcome in Elderly People during the 2014 Outbreak in Guinea

被引：0

作者：

Cherif, Mahamoud Sama ^{[1
,2
,5
,6
]}

Dumre, Shyam Prakash ^{[2
,5
]}

Kasse, Dienaba ^{[1
,7
]}

Cherif, Fatoumata ^{[3
,8
]}

Camara, Facely ^{[1
,7
]}

Kone, Alpha ^{[1
,7
]}

Diakite, Mandiou ^{[1
,7
]}

Cisse, Mohamed ^{[1
,7
]}

Diallo, Mamadou Pathe ^{[1
,7
]}

Le Gall, Edouard ^{[1
,4
,7
]}

Karbwang, Juntra ^{[2
,9
]}

Hirayama, Kenji ^{[2
,5
]}

机构：

[1] Gamal Abdel Nasser Univ Conakry, Fac Med Pharm & Odontostomatol, BP 1147, Conakry, Guinea

[2] Nagasaki Univ, Inst Trop Med NEKKEN, Nagasaki, Japan

[3] Minist Hlth & Publ Hyg, Conakry, Guinea

[4] Pole Reg Cancerol Bretagne, Rennes, France

[5] Nagasaki Univ, Inst Trop Med, Dept Immunogenet, Nagasaki, Japan

[6] Univ Gamal Abdel Nasser Conakry, Dept Med, Commune Dixinn, Conakry, Guinea

[7] Univ Gamal Abdel Nasser Conakry, Dept Med, Conakry, Guinea

[8] Agence Natl Secur Sanit, Minist Hlth & Publ Hyg, Conakry, Guinea

[9] Nagasaki Univ, Inst Trop Med, Dept Prod Dev, Nagasaki, Japan

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2018年 / 98卷 / 01期

关键词：

SIERRA-LEONE; MORTALITY;

D O I：

10.4269/ajtmh.17-0372

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Elderly people occupy a prominent position in African societies; however, their potential linkage to high case fatality rate (CFR) in Ebola virus disease (EVD) was often overlooked. We describe the predictive factors for EVD lethality in the elderly. A total of 2,004 adults and 309 elderly patients with confirmed EVD were included in the analysis. The median age (interquartile range) was 35 years (23-44) in adults and 65 years (60-70) in the elderly. The proportion of funeral participation was significantly higher in the elderly group than in the adult group. Duration (in days) between the onset of symptoms and admission was significantly longer in elderly. CFR in the elderly people was also significantly higher (80.6%) than in the adult group (66.2%). Funeral participation constituted a risk factor for the transmission of EVD in elderly people.

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页码：198 / 202

页数：5

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