Enhanced radioiodine uptake in a patient with poorly differentiated papillary thyroid cancer after treatment with rosiglitazone

被引：17
|
作者：
Elias, Alan N.
Lizotte, Paul
机构：
[1] Univ Calif Irvine, Med Ctr, Dept Med, Orange, CA 92868 USA
[2] Univ Calif Irvine, Med Ctr, Dept Radiol, Orange, CA 92868 USA
来源：
CLINICAL NUCLEAR MEDICINE | 2006年 / 31卷 / 09期
关键词：
PPAR; rosiglitazone; thyroid cancer; differentiation therapy;
D O I：
10.1097/01.rlu.0000233148.45744.44
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
The effect of pretreatment with the peroxisome proliferator-activated receptor (PPAR) agonist, rosiglitazone, on radioiodine uptake and serum thyroglobulin levels in a patient with radioiodine-resistant papillary thyroid cancer is described. Treatment with rosiglitazone resulted in enhanced radioiodine uptake in areas of presumed metastatic disease in the neck that were previously only faintly seen, and serum thyroglobulin fell from a pretreatment level of 41 ng/mL to less than 2 ng/mL.
引用
收藏
页码：517 / 519
页数：3
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