Absence of human metapneumovirus co-infection in cases of severe respiratory syncytial virus infection

被引:46
|
作者
van Woensel, J. B. M.
Bos, A. P.
Lutter, R.
Rossen, J. W. A.
Schumman, R.
机构
[1] Emma Childrens Hosp, Pediat Intens Care Unit, Acad Med Ctr, NL-1100 DD Amsterdam, Netherlands
[2] Acad Med Ctr, Dept Pulmonol & Expt Immunol, NL-1100 DD Amsterdam, Netherlands
[3] Univ Med Ctr Utrecht, Eijkman Winkler Ctr, Dept Virol, Utrecht, Netherlands
关键词
respiratory syncytial virus; human metapneumovirus; lower respiratory tract infection;
D O I
10.1002/ppul.20459
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
It has been suggested that co-infection of human metapneurnovirus (hMPV) in severe respiratory syncytial (RSV) virus bronchiolitis is very common. To evaluate the epidemiology of hMPV co-infection in children with severe lower respiratory tract infection caused by RSV virus. This was an observational cohort study in which hMPV and RSV viral load was measured by RT-PCR in tracheal specimens from the target population. hMPV could not be detected in any of the 30 mechanically ventilated children with RSV lower respiratory tract infection. Our study suggests that hMPV co-infection is not very common in severe RSV lower respiratory tract infection.
引用
收藏
页码:872 / 874
页数:3
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