Spectroscopic characterization of bone tissue of experimental animals after glucocorticoid treatment and recovery period

被引：2

作者：

Mitic, Zarko J. ^{[1
]}

Najman, Stevo J. ^{[1
]}

Cakic, Milorad D. ^{[2
]}

Ajdukovic, Zorica R. ^{[1
]}

Ignjatovic, Nenad L. ^{[3
]}

Nikolic, Ruzica S. ^{[4
]}

Nikolic, Goran M. ^{[1
]}

Stojanovic, Sanja T. ^{[1
]}

Vukelic, Marija D. ^{[1
]}

Trajanovic, Miroslav D. ^{[5
]}

机构：

[1] Univ Nis, Fac Med, RS-18000 Nish, Serbia

[2] Univ Nis, Fac Technol, RS-16000 Leskovac, Serbia

[3] Serbian Acad Arts & Sci, Inst Tech Sci, RS-11000 Belgrade, Serbia

[4] Univ Nis, Fac Sci & Math, RS-18000 Nish, Serbia

[5] Univ Nis, Fac Mech Engn, RS-18000 Nish, Serbia

来源：

JOURNAL OF MOLECULAR STRUCTURE | 2014年 / 1074卷

关键词：

FTIR; MS; Mandible; Glucocorticoids; Minerals; CALCIUM-PHOSPHATE; CORTICAL BONE; IN-VITRO; OSTEOPOROSIS; HYDROXYAPATITE; COMPOSITE; COLLAGEN; CALCITONIN; BIOMATERIALS; GROWTH;

D O I：

10.1016/j.molstruc.2014.06.006

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The influence of glucocorticoids on the composition and mineral/organic content of the mandible in tested animals after recovery and healing phase was investigated in this work. The results of FTIR analysis demonstrated that bone tissue composition was changed after glucocorticoid treatment. The increase of calcium, magnesium, phosphorus content and mineral part of bones was statistically significant in recovery phase and in treatment phase that included calcitonin and thymus extract. Some changes also happened in the organic part of the matrix, as indicated by intensity changes for already present IR bands and the appearance of new IR bands in the region 3500-1300 cm(-1). (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：315 / 320

页数：6

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