Fabrication of Cost-Effective Surface Enhanced Raman Spectroscopy Substrate Using Glancing Angle Deposition for the Detection of Urea in Body Fluid

被引：14

作者：

Han, Yun-Ah ^{[1
]}

Ju, Jonghyun ^{[1
]}

Yoon, Yoosik ^{[2
]}

Kim, Seok-Min ^{[1
]}

机构：

[1] Chung Ang Univ, Sch Mech Engn, Seoul 156756, South Korea

[2] Chung Ang Univ Coll Med, Dept Microbiol, Seoul 156756, South Korea

来源：

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | 2014年 / 14卷 / 05期

基金：

新加坡国家研究基金会;

关键词：

Surface Enhanced Raman Spectroscopy; Glancing Angle Deposition; Ag Nanorods; NANOPARTICLES; FILMS;

D O I：

10.1166/jnn.2014.8184

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A surface enhanced Raman spectroscopy (SEAS) with glancing angle deposited Ag nanorods structures was developed for the detection of urea in human serum. To maximize the SERS enhancement, the effects of Ag nanorod length on the SERS signal were analyzed. The SERS signals of different concentrations of urea solutions were measured in order to generate a regression model for use in analyzing the amount of urea in body fluid using the SEAS substrate. To examine the feasibility of the fabricated SEAS substrate, the amount of urea in human serum was measured using the SEAS substrate and compared with that determined via conventional blood analysis.

引用

页码：3797 / 3799

页数：3

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