Synthesis and antitumor activity of puupehedione and related compounds

被引：79
|
作者：
Barrero, AF [1 ]
Alvarez-Manzaneda, EJ
Chahboun, R
Cortés, M
Armstrong, V
机构：
[1] Univ Granada, Fac Ciencias, Dept Quim Organ, E-18071 Granada, Spain
[2] Pontificia Univ Catolica Chile, Fac Quim, Dept Quim Organ, Santiago 22, Chile
来源：
TETRAHEDRON | 1999年 / 55卷 / 52期
关键词：
terpenes; antitumour compounds; marine metabolites;
D O I：
10.1016/S0040-4020(99)00992-8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The first enantiospecific synthesis of bioactive marine puupehedione (2) and related compounds from (-)-sclanol (11) is reported. The antitumor activity of these compounds was assayed and compared with that of the natural products. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：15181 / 15208
页数：28
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