BACKGROUND: Discharging patients from the intensive care unit (ICU) often requires complex decision making to balance patient needs with available resources. Unplanned return to the ICU("bounce back" [BB]) has been associated with increased resource use and worse outcomes, but few data on trauma patients are available. The goal of this study was to review ICU BB and define ICU discharge variables that may be predictive of BB. METHODS: Adults admitted to ICU and discharged alive to a ward from November 04, 2012, to September 9, 2012 (interval with no changes in coverage), were selected from our trauma registry. Patients with unplanned return to ICU (BB cases) were matched 1: 2 with controls on age, Injury Severity Score (ISS), and duration of post-ICU stay. Data were collected by chart review then analyzed with univariate and conditional multivariate techniques. RESULTS: Of 8,835 hospital admissions, 1,971 (22.3%) were discharged alive from ICU to a ward. Eighty-eight patients (4.5%) met our criteria for BB(male, 75%; mean [SD] age, 52.9 [21.9] years; mean [SD] ISS, 23.1 [10.2]). Most (71.6%) occurred within 72 hours. Mortality for BB cases was high (19.3%). Regression analysis showed that male sex (odds ratio, 2.9; p = 0.01), Glasgow Coma Scale [GCS] score of less than 9 (odds ratio, 22.3; p < 0.01), discharge during day shift (odds ratio, 6.9; p < 0.0001), and presence of one (odds ratio, 3.5; p = 0.03), two (odds ratio, 3.8; p = 0.03), or three or more comorbidities (odds ratio, 8.4; p < 0.001) were predictive of BB. CONCLUSION: In this study, BB rate was 4.8%, and associated mortality was 19.3%. At the time of ICU discharge, male sex, a GCS score of less than 9, higher FIO2, discharge on day shift, and presence of one or more comorbidities were the strongest predictors of BB. A multi-institutional study is needed to validate and extend these results. (Copyright (C) 2013 by Lippincott Williams & Wilkins)